Results 81 to 90 of about 6,202,666 (342)
Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Career counseling research-practice disparities: What we know and what we need to know
South African Journal of Education, 2017 The most practical principle in contextualisation emanates from our understanding of the experience of everyday life. However, this principle is not confined to such understanding.
Maria Eduarda Duarte
doaj +1 more source
Formalized Mathematics, 2014 Summary Two construction functors: simple term with a variable and compound term with an operation and argument terms and schemes of term induction are introduced. The degree of construction as a number of used operation symbols is defined. Next, the term context is investigated.
openaire +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Les transformations actuelles de l’EEE
Mesure et Évaluation en Éducation, 2012 Dans cet article conclusif, les transformations actuelles de l’EEE sont interrogées selon trois axes. Les limites et les dérives observées dans ce domaine conduisent tout d’abord à remettre en question une approche de la qualité de l’enseignement ...
Nathalie Younès, Marc Romainville
doaj +1 more source
Editorial: Context in Context [PDF]
Foundations of Science, 2002 Edmonds, B., Akman, V.
openaire +2 more sources
Languages for Specific Purposes in the United States in a Global Context: Commentary on Grosse and Voght (1991) Revisited [PDF]
, 2012 Barbara A Lafford
openalex +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source