Results 181 to 190 of about 1,353,434 (288)

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Efficient Approach to Color Image Segmentation Based on Multilevel Thresholding Using EMO Algorithm by Considering Spatial Contextual Information. [PDF]

J Imaging, 2023
Rangu S, Veramalla R, Salkuti SR, Kalagadda B.   +3 more
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Atypical cortical feedback underlies failure to process contextual information in the superior colliculus of Scn2a^+/- autism model mice. [PDF]

Nat Commun
Ferrarese L, Asari H.
europepmc   +1 more source

Contextual information in medicolegal death investigation decision-making: Manner of death determination for cases of a single gunshot wound. [PDF]

Forensic Sci Int Synerg, 2022
Dror IE, Wolf DA, Phillips G, Gao S, Yang Y, Drake SA.   +5 more
europepmc   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

RBPSpot: Learning on appropriate contextual information for RBP binding sites discovery. [PDF]

iScience, 2021
Sharma NK, Gupta S, Kumar A, Kumar P, Pradhan UK, Shankar R.   +5 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Prior contextual information and autistic traits influence eye gaze behaviour and emotional valence ratings for facial expressions. [PDF]

Sci Rep
Karakale Ö, Nelson N, Gredelj A, Ryan KJ, Bayindir A.   +4 more
europepmc   +1 more source

Breast Mass Classification Using Diverse Contextual Information and Convolutional Neural Network. [PDF]

Biosensors (Basel), 2021
Busaleh M, Hussain M, Aboalsamh HA, Amin FE.   +3 more
europepmc   +1 more source