Results 91 to 100 of about 17,795 (314)

Les intentions d’écriture de Montaigne

open access: yesMethodos, 2016
Readings of Montaigne most frequently taught build some artifacts (Montaigne anthropologist, Montaigne centered on its “me”, etc.) and underline the determining weight of the context and of the biography in the production of the Essais.
Jean-François Dupeyron
doaj   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig   +9 more
wiley   +1 more source

Transformers, Contextualism, and Polysemy

open access: yesErgo, An Open Access Journal of Philosophy
The transformer architecture, introduced by Vaswani et al. (2017), is at the heart of the remarkable recent progress in the development of language models, including widely-used chatbots such as Chat-GPT and Claude.
Jumbly Grindrod
doaj   +2 more sources

Perspectival Plurality, Relativism, and Multiple Indexing [PDF]

open access: yes, 2018
In this paper I focus on a recently discussed phenomenon illustrated by sentences containing predicates of taste: the phenomenon of " perspectival plurality " , whereby sentences containing two or more predicates of taste have readings according to which
Zeman, Dan
core  

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

The Relationship between Dewey\'s Moral Contextualism and Kant\'s Deontological Ethics in Abortion [PDF]

open access: yesInternational Journal of Ethics and Society, 2023
Introduction: Abortion is related to local ethics and is one of the situations in which all conditions and cases should be taken into account. In this article, by examining John Dewey's opinions about Kant's contextualism and deontology, the issue of ...
Ghasem Fardid   +2 more
doaj  

The Essential Contextual [PDF]

open access: yes, 2011
Standard accounts of self-locating or essentially indexical knowledge and belief (such as that of David Lewis) make it difficult to understand the communication of self-locating information. But even the amnesiacs who populate the examples in the literature on this issue can talk with others about who they are or might be, and a general account of ...
openaire   +2 more sources

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

The Association of Physical Function With Psychosocial Patient‐Reported Outcomes in People With Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate how modifiable psychosocial factors and fatigue relate to physical functioning in patients with systemic lupus erythematosus (SLE). Methods In this cross‐sectional study of two demographically distinct cohorts (Approaches to Positive, Patient‐Centered Experiences of Aging with Lupus [APPEAL] and California Lupus Epidemiology Study
Mrinalini Dey   +8 more
wiley   +1 more source

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