Results 71 to 80 of about 17,795 (314)
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
, 2020 Contextualist treatments of clashes of intuitions can allow that two claims, apparently in conflict, can both be true. But making true utterances is far from the only thing that matters — there are often substantive normative questions about what ...
Ichikawa, Jonathan
core
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Ergo, An Open Access Journal of PhilosophyIf you ought to do something, does it follow that you are able to do it? The Kantian thesis that ought-implies-can seems intuitive and is widely accepted. Nevertheless, there are several powerful purported counterexamples.
Darren Bradley
doaj +2 more sources
A contextualist treatment of the predicate of existence
Filosofia Unisinos, 2021 I first give a very short characterization of contextualism in the philosophy of language; then I present the traditional debate about the question whether “exists” is a first or second order predicate, to conclude, firstly, that there is a first order ...
André Leclerc
doaj
Contextual Word Representations: A Contextual Introduction
CoRR, 2019 This introduction aims to tell the story of how we put words into computers. It is part of the story of the field of natural language processing (NLP), a branch of artificial intelligence. It targets a wide audience with a basic understanding of computer programming, but avoids a detailed mathematical treatment, and it does not present any algorithms ...
openaire +2 more sources
Quantum, 2023 Quantum contextual sets have been recognized as resources for universal quantum computation, quantum steering and quantum communication. Therefore, we focus on engineering the sets that support those resources and on determining their structures and properties.
openaire +5 more sources
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Contextualism, skepticism, and invariantism
Principia: An International Journal of Epistemology, 2010 Michael Williams and Keith DeRose defend their different versions of contextualism on the grounds that contextualism gives a better account of the ordinary use of epistemic terms than invariantist competitors.
Stephen Jacobson
doaj
, 2019 How should we account for the contextual variability of knowledge claims? Many philosophers favour an invariantist account on which such contextual variability is due entirely to pragmatic factors, leaving no interesting context-sensitivity in the ...
Kindermann, Dirk
core +1 more source