Results 51 to 60 of about 1,577 (257)

Time to Diagnosis Among Children and Adolescents With Cancer in Québec, Canada: A Population‐Based Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen   +5 more
wiley   +1 more source

Complexity of contextuality

open access: yesPhysical Review A
Generalized contextuality is a hallmark of nonclassical theories like quantum mechanics. Yet, three fundamental computational problems concerning its decidability and complexity remain open: first, determining the complexity of deciding if a theory admits a noncontextual ontological model; second, determining the complexity of ...
Theodoros Yianni, Farid Shahandeh
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Wigner Function Negativity and Contextuality in Quantum Computation on Rebits

open access: yesPhysical Review X, 2015
We describe a universal scheme of quantum computation by state injection on rebits (states with real density matrices). For this scheme, we establish contextuality and Wigner function negativity as computational resources, extending results of M.
Nicolas Delfosse   +3 more
doaj   +1 more source

Generalized Householder Transformations

open access: yesEntropy, 2022
The Householder transformation, allowing a rewrite of probabilities into expectations of dichotomic observables, is generalized in terms of its spectral decomposition.
Karl Svozil
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Spirituality and contextuality

open access: yesActa Theologica, 2006
This article discusses various historiographies of spirituality as an indication of the influence of context on spirituality. It gives an overview of the most important historiographies of spirituality.
K. Waaijman
doaj   +1 more source

Contextualizing concepts.

open access: yesCoRR, 2002
To cope with problems arising in the description of (1) contextual interactions, and (2) the generation of new states with new properties when quantum entities become entangled, the mathematics of quantum mechanics was developed. Similar problems arise with concepts.
Gabora, Liane, Aerts, Diederik
openaire   +4 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Logical pre- and post-selection paradoxes are proofs of contextuality [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2015
If a quantum system is prepared and later post-selected in certain states, "paradoxical" predictions for intermediate measurements can be obtained. This is the case both when the intermediate measurement is strong, i.e.
Matthew F. Pusey, Matthew S. Leifer
doaj   +1 more source

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