Results 71 to 80 of about 20,860 (278)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Constraint contextual rewriting
Journal of Symbolic Computation, 2003 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
ARMANDO, ALESSANDRO, RANISE S.
openaire +2 more sources
Simple Hardy-like proof of quantum contextuality
, 2013 Contextuality and nonlocality are two fundamental properties of nature. Hardy's proof is considered the simplest proof of nonlocality and can also be seen as a particular violation of the simplest Bell inequality.
Badziag, Piotr +3 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Quantum nonlocality via local contextuality with qubit-qubit entanglement
, 2016 Quantum nonlocality can be revealed "via local contextuality" in qudit-qudit entangled systems with $d > 2$, that is, through the violation of inequalities containing Alice-Bob correlations that admit a local description, and Alice-Alice correlations ...
Cabello, Adán +3 more
core +1 more source
Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer
Aging and Cancer, EarlyView.Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss +12 more
wiley +1 more source
Causation does not explain contextuality [PDF]
Quantum, 2018 Realist interpretations of quantum mechanics presuppose the existence of elements of reality that are independent of the actions used to reveal them. Such a view is challenged by several no-go theorems that show quantum correlations cannot be explained ...
Sally Shrapnel, Fabio Costa
doaj +1 more source
State-independent experimental test of quantum contextuality in an indivisible system
, 2012 We report the first state-independent experimental test of quantum contextuality on a single photonic qutrit (three-dimensional system), based on a recent theoretical proposal [Yu and Oh, Phys. Rev. Lett. 108, 030402 (2012)].
A. Peres +9 more
core +1 more source
Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz +3 more
wiley +1 more source