Results 61 to 70 of about 4,515 (300)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Measuring contextuality in investment preferences [PDF]
This study investigates the role of contextuality in investment preference formation, specifically in global investments and major US stocks. Utilizing the "Contextuality by Default" framework (Dzhafarov and Kujala in PLoS ONE 8:e61712, 2013; J Math ...
Khrennikova, Polina; id_orcid +1 more
core +1 more source
A classification of multipartite states by degree of non-locality [PDF]
Electronic Proceedings in Theoretical Computer Science, 2014 We propose a novel form of classification of multipartite states, in terms of the maximum degree of non-locality they can exhibit under any choice of local observables.
Samson Abramsky, Carmen Constantin
doaj +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
New Journal of Physics, 2023 Contextuality is a striking feature of our nature predicted by quantum theory and tested by various experiments. In a qubit system, testing contextuality requires scenarios distinct from traditional ones for systems with dimension of three or greater. In
Meng Yan, Hao-Zhan Zou, Xiang Zhan
doaj +1 more source
Physical Review AGeneralized contextuality is a hallmark of nonclassical theories like quantum mechanics. Yet, three fundamental computational problems concerning its decidability and complexity remain open: first, determining the complexity of deciding if a theory admits a noncontextual ontological model; second, determining the complexity of ...
Theodoros Yianni, Farid Shahandeh
openaire +2 more sources
Quantum advantage from sequential transformation contextuality [PDF]
, 2018 We introduce a notion of contextuality for transformations in sequential contexts, distinct from the Bell-Kochen-Specker and Spekkens notions of contextuality.
Mansfield, Shane, Kashefi, Elham
core +1 more source
Can There be Given Any Meaning to Contextuality Without Incompatibility?
, 2021 Our aim is to compare the fundamental notions of quantum physics - contextuality vs. incompatibility. One has to distinguish two different notions of contextuality, Bohr-contextuality and Bell-contextuality.
Khrennikov, Andrei,
core +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Wigner Function Negativity and Contextuality in Quantum Computation on Rebits
Physical Review X, 2015 We describe a universal scheme of quantum computation by state injection on rebits (states with real density matrices). For this scheme, we establish contextuality and Wigner function negativity as computational resources, extending results of M.
Nicolas Delfosse +3 more
doaj +1 more source