Results 81 to 90 of about 5,086 (256)

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

open access: yesAdvanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes   +15 more
wiley   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

open access: yesAdvanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio   +6 more
wiley   +1 more source

Agricultural Producers' Willingness to Pay for Real-Time Mesoscale Weather Information: A Response

open access: yesJournal of Agricultural and Resource Economics, 1997
Philip L. Kenkel, Patricia E. Norris
doaj   +1 more source

Brain‐Computer Interface Training Fosters Perceptual Skills to Detect Errors

open access: yesAdvanced Science, EarlyView.
Accurate perception of visuomotor errors underpins motor precision and learning, yet conventional behavioral training fails to improve sensitivity to subtle errors. Real‐time EEG‐based brain‐computer interface feedback targeting the error positivity component enhances perceptual learning of small errors.
Deland H. Liu   +4 more
wiley   +1 more source

Optical Windows for Transcranial Brain Imaging in Living Mice: Skull Thinning, Clearing, and Beyond

open access: yesAdvanced Science, EarlyView.
Longitudinal, noninvasive in vivo imaging is crucial for studying brain physiology. Advances in transcranial optical windows and multiphoton microscopy have improved imaging depth, but their performance often deteriorates over time. This work investigated various transcranial window approaches and found that skull regrowth limits image quality.
Yiming Fu   +5 more
wiley   +1 more source

Valuation of the Trang An karst system using contingent valuation method and choice experiment

open access: yesDiscover Sustainability
Trang An Landscape Complex is a World Cultural and Natural Heritage with outstanding universal value owing to its remarkable scenery and rich traditional culture.
Nguyen Thi Vinh Ha   +4 more
doaj   +1 more source

Halide Perovskite: A Rich Source of Thermal Insulator

open access: yesAdvanced Science, EarlyView.
Halide perovskites exhibit ultralow thermal conductivity driven by intrinsic lattice softness and strong anharmonicity, falling below conventional defect‐engineering limits. Weak metavalent bonding, A‐site rattling, and dynamic octahedral tilting drive phonon scattering to the Ioffe–Regel limit, where wave‐like tunneling replaces particle‐like ...
Haolin Ye   +3 more
wiley   +1 more source

Which monetary values for the quality of our environment? The example of pollution in the Krška kotlina alluvial aquifer in Slovenia

open access: yesGeologija, 2009
The increasing integration of economic issues into environmental policy has put the valuation of environmentalgoods and services at the forefront of the agenda of experts and researchers involved in the design and implementationof this policy.
Joerg Prestor   +4 more
doaj  

Willingness to pay for antiretroviral therapy, viral load, and premium services; A contingent valuation survey of people living with HIV in southern Nigeria. [PDF]

open access: yesPLoS One, 2023
Sanwo O   +14 more
europepmc   +1 more source

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