Results 91 to 100 of about 5,130,669 (296)

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

On convergence $(2,1,\dots,1)$-periodic branched continued fraction of the special form

open access: yesKarpatsʹkì Matematičnì Publìkacìï, 2015
$(2,1,\dots,1)$-periodic branched continued fraction of the special form is defined. Conditions of convergence are established for 2-periodic continued fraction and $(2,1,\dots,1)$-periodic branched continued fraction of the special form.
D.I. Bodnar, M.M. Bubniak
doaj   +1 more source

Continued Fractions and Linear Fractional Transformations

open access: yes, 2014
Rational approximations to a square root $\sqrt{k}$ can be produced by iterating the transformation $f(x) = (dx+k)/(x+d)$ starting from $\infty$ for any positive integer $d$. We show that these approximations coincide infinitely often with continued fraction convergents if and only if $4d^2/(k-d^2)$ is an integer, in which case the continued fraction ...
openaire   +3 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

A spectrum associated with Minkowski diagonal continued fraction

open access: yes, 2011
We prove a result on the structure of a Diophantine spectrum associated with Minkowski diagonal continued ...
Aleksenko, Alena
core  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Prime numbers in typical continued fraction expansions. [PDF]

open access: yesBoll Unione Mat Ital (2008), 2023
Schindler TI, Zweimüller R.
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Classical homogeneous multidimensional continued fraction algorithms are ergodic

open access: yes, 2013
Homogeneous continued fraction algorithms are multidimensional generalizations of the classical Euclidean algorithm, the dissipative map $$ (x_1,x_2) \in \mathbb{R}_+^2 \longmapsto \left\{\begin{array}{ll} (x_1 - x_2, x_2), & \mbox{if $x_1 \geq x_2$}
Chaika, Jonathan, Nogueira, Arnaldo
core   +1 more source

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