Results 31 to 40 of about 1,782,235 (304)

Evaluation of the Hemostatic Activity of Multicomponent Polymer Sponge Implants in An In Vitro Experiment

Неотложная медицинская помощь
BACKGROUND. The development of new samples of local hemostatic agents is an intensively developing area of the modern industrial biotechnology due to a high need of clinical bases for such products.
V. A. Lipatov, S. V. Lazarenko, D. A. Severinov, A. A. Denisov, O. V. Padalkina   +4 more
doaj   +1 more source

A Flexible Regimen of Combination Antihypertensive Therapy for Lower Blood Pressure to the Lower Target Level. Viewpoint of Cardiologist and Clinical Pharmacologist

Рациональная фармакотерапия в кардиологии, 2019
Modern tactics of antihypertensive therapy with fixed dose combination or with free combinations of antihypertensive drugs are reviewed in the article. The evidence that a flexible regimen of combination antihypertensive therapy is more reasonable in the
S. R. Gilyarevskiy, M. V. Golshmid, G. Yu. Zaharova, I. M. Kuzmina, I. I. Sinitsina   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Challenging the orthodoxy: union learning representatives as organic intellectuals [PDF]

, 2008
Teacher education and continuing professional development have become a key areas of controversy in England since the period of school sector restructuring following the 1988 Education Reform Act.
Alexandrou A., Ball S., Barber M., Clough B., Fryer R., Gewirtz S., Gramsci A., Howard Stevenson, Hyman R., Ironside M., Kerchner C., Kerchner C., Naylor C., Simon B., Stevenson H., Stevenson H., Togliatti P., Wood H.   +17 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Mandatory Continuing Education: Does It Really Protect Society from Incompetent Health Professionals [PDF]

, 1990
Although the focus is narrow, this article argues that, in the face of short half-lives of current knowledge, continuing education requirements are needed and suggests possible improvements in the way that continuing education is implemented.
McPartland, Patricia A.
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Interpreting in Palliative Care: A Continuing Education Workshop [PDF]

, 2011
Offers a curriculum for a daylong course for interpreters about palliative care, including lesson plans, handouts, presentation slides, and ...
Alicia Fernandez, Anne Kinderman, Cynthia Roat   +2 more
core  

Health care professionals' perceptions towards lifelong learning in palliative care for general practitioners: a focus group study [PDF]

, 2014
Background: There is a growing need for palliative care. The majority of palliative patients prefer their general practitioner (GP) to organize their palliative home care. General practitioners need a range of competences to perform this task.
Deveugele, Myriam, Pype, Peter, Stes, Ann, Symons, Linda, Van den Eynden, Bart, Wens, Johan   +5 more
core   +2 more sources