Results 41 to 50 of about 1,782,235 (304)

Probiotic Lactobacillus reuteri DSM 17938: what is known about it today?

Медицинский совет, 2019
The review is devoted to the analysis of data on the effects of Lactobacillus reuteri DSM 17938, confirmed in clinical trials. Thanks to their antimicrobial activity, L. reuteri is able to inhibit colonization by pathogenic microorganisms and restore the
I. N. Zakharova, I. V. Berezhnaya, A. Е. Kuchina, O. V. Dedikova   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Analysis of health service utilization of migrants in Beijing using Anderson health service utilization model

BMC Health Services Research, 2018
Background Migrants are the unique production of China’s urbanization process. They are often excluded from social welfare and security systems of cities, and often exposed to high health risk related closely to their health problems.
Shuang Shao, Meirong Wang, Guanghui Jin, Yali Zhao, Xiaoqin Lu, Juan Du   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Model for Predicting the Risk of Developing Drug-Induced Liver Injury During Therapy with Favipiravir

Антибиотики и Химиотерапия
Favipiravir is an antiviral drug that has become widely used for the etiotropic treatment of COVID-19. According to a number of studies, the incidence of adverse reactions during favipiravir therapy reaches 93%, and the most common adverse reaction is an
Yu. V. Shevchuk, I. V. Sychev, A. V. Kryukov, I. I. Temirbulatov, K. B. Mirzaev, N. P. Denisenko, Sh. P. Abdullaev, S. N. Tuchkova, V. I. Vechorko, O. V. Averkov, D. A. Sychev   +10 more
doaj   +1 more source

The training contents, problems and needs of doctors in urban community health service institutions in China

BMC Family Practice, 2018
Background The Chinese government offered various types of training programs for strengthening the role of doctors working in community health service institutions (CHSIs).
Shuang Shao, Tao Wu, Aimin Guo, Guanghui Jin, Rui Chen, Yali Zhao, Juan Du, Xiaoqin Lu   +7 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Scottish higher education : a continuing debate [PDF]

, 2012
The period since the May 2011 Holyrood elections has seen a continuation of the debate over the future of Scottish Higher Education. This debate has contained several elements, including: continuing commitment to the policy of not charging tuition fees ...
Love, James
core  

Communication technologies and education: Lessons in the potential of innovation [PDF]

, 1997
The evaluation of initiatives in using new forms of technology to enhance teaching and learning will raise awareness of the need for a structured and principled approach to the introduction of innovative methods.
Norman, Nigel
core   +4 more sources