Results 101 to 110 of about 750,466 (305)

On Darboux continuity and continuity

open access: yesJournal of Mathematical Analysis and Applications, 1981
AbstractLipinski's (Colloq. Math.19 (1968), 251–253) theorem for a Darboux function to be continuous is extended and a question raised by him is partially answered.
Pu, H.W, Pu, H.H
openaire   +2 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

ContinuITy-Project/forecastic: Release at project end (v0.5.3)

open access: yes, 2020
Forecastic is a workload forecasting service implemented in R for ContinuITy, which is the open-source implementation of a research project on "Automated Performance Testing in Continuous Software Engineering", launched by Novatec Consulting GmbH and the
Henning Schulz
core   +1 more source

Non-Stationary Representation for Continuity Aware Head Pose Estimation Via Deep Neural Decision Trees

open access: yesIEEE Access, 2019
The problem of image-based head pose estimation attracts intensive attention due to a large number of applications such as face analysis and attention modeling. Existing methods often convert head pose estimation into the pose classification problem, but
Jiang Wang   +3 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Continuity of Learning background paper, UNICEF Pakistan

open access: yes, 2021
In aid of the continuity of learning during and after the COVID-19 pandemic, this continuity of learning background paper has three objectives: - to offer guidelines to support the provision of home-based learning for children during the COVID-19 ...
Couch, Daniel
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

To continue or not to continue?

open access: yes
Nearly half of all people in the Netherlands will experience a psychiatric disorder at some point in their lives. So how can we ensure that treatment truly fits the unique person?This dissertation shows that mental disorders develop differently in women than in men.
openaire   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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