Results 121 to 130 of about 584,519 (316)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Other title: Kansas Continuity of Operations Planning Committee meeting agendas and minutes, 2015-2016

open access: yes, 2015
Application/pdf."The Kansas Continuity of Operations (COOP) Planning Committee is committed to cooperatively addressing the challenges of developing Continuity of Operations Plans at the state agency level.
Kansas Continuity of Operations (COOP) Planning Committee.
core  

To continue or not to continue?

open access: yes
Nearly half of all people in the Netherlands will experience a psychiatric disorder at some point in their lives. So how can we ensure that treatment truly fits the unique person?This dissertation shows that mental disorders develop differently in women than in men.
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A utility representation theorem with weaker continuity condition

open access: yes, 2008
Inoue T. A utility representation theorem with weaker continuity condition. Working Papers. Institute of Mathematical Economics. Vol 401. Bielefeld: Universität Bielefeld; 2008.We prove that a preference relation which is continuous on every straight ...
Inoue, Tomoki
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

แผนบริหารความพร้อมต่อสภาวะวิกฤติ (Business Continuity Plan : BCP) ของส่วนราชการสังกัดรัฐสภา ประจำปีงบประมาณ พ.ศ. 2564-2565

open access: yes, 2020
ปก สารบัญ บทที่ 1 ความเป็นมา -1.1 ความเป็นมา -1.2 วัตถุประสงค์ (objectives) -1.3 สมมติฐานของแผนบริหารความพร้อมต่อสภาวะวิกฤติ (BCP Assumptions) -1.4 ขอบเขตของแผนบริหารความพร้อมต่อสภาวะวิกฤติ (Scope of BCP) -1.5 การใช้แผนบริหารความพร้อมต่อสภาวะวิกฤติ (BCP)
คณะกรรมการดำเนินการตามแผนบริหารความพร้อมต่อสภาวะวิกฤติ (Business Continuity Management : BCM) ของส่วนราชการสังกัดรัฐสภา
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Managing continuity: dealing with the experience of being target in a take-over. [PDF]

open access: yes
Based upon literature on innovation and strategy, the experience of being target in a take-over is studied from a process perspective at a local office of the acquired parent company.
Overlaet, Robrecht, Bouwen, Jan
core  

Feasibility of tele-rehabilitation in survivors of COVID-19 pneumonia

open access: yesPulmonology, 2022
M. Paneroni   +4 more
doaj   +1 more source

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