Results 81 to 90 of about 2,020,326 (291)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
On the Hölder continuity for a class of vectorial problems
Advances in Nonlinear Analysis, 2019 In this paper we prove local Hölder continuity of vectorial local minimizers of special classes of integral functionals with rank-one and polyconvex integrands.
Cupini Giovanni +3 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Metaphor patterns in Sesotho fiction: The case of the novel Chaka
Tydskrif vir LetterkundeIn this study, we examine the nature, distribution, and stylistic effect of metaphors used in the Sesotho novel Chaka. Previous studies have discussed the metaphoric language in Thomas Mofolo’s work, revealing that, among others, Mofolo uses metaphors ...
Ntšoeu Seepheephe +1 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
ПравоприменениеThe monograph of the prominent Russian constitutionalist Yuri Skuratov "Problems of State and Legal Development of Russia: Scientist's View and Practice. Selected Works" (Moscow, Gubkin Russian State University of Oil and Gas Publ., 2023. 637 p.).
N. A. Bobrova
doaj +1 more source
Remote Sensing, 2014 The new Landsat-8 Operational Land Imager (OLI) is intended to be broadly compatible with the previous Landsat-7 Enhanced Thematic Mapper Plus (ETM+).
Neil Flood
doaj +1 more source