Results 91 to 100 of about 369,296 (309)

Continuity of care: the patient perspective

The Bulletin of the Royal College of Surgeons of England, 2009
As part of this issue's special theme on continuity of care, the current article treats the topic from the perspective of the surgical patient. Lesley Bentley, of the College's Patient Liaison Group, draws on her own experience of the pathway to highlight the importance of continuity at all stages in the patient journey.
openaire   +1 more source

Comparing importance and performance from a patient perspective in English general practice: a cross-sectional survey [PDF]

, 2016
Background. Patient experience and satisfaction are important indicators of quality in health care. Little is known about where to prioritize efforts to improve patient satisfaction. Objectives. To investigate patient satisfaction with primary care, as
Godoy Caballero, Ana, Jackson, Christine, McKay, Steve, Schäfer, Willemijn, Sirdifield, Coral, Siriwardena, A. Niroshan, Windle, Karen   +6 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

DISCHARGE MANAGEMENT TO ENSURE CONTINUITY OF CARE: EXPERIENCE OF PORTUGUESE LIAISON NURSES

Cogitare Enfermagem, 2018
Objective: To describe the activities performed to ensure continuity of care by liaison nurses in hospital services. Method: Descriptive exploratory study with 107 nurses conducted from September 2016 to March 2017, in 15 hospitals in Portugal.
Maria Manuela Martins, Gisele Knop Aued, Olga Maria Pimenta Lopes Ribeiro, Maria José Santos, Maria Ribeiro Lacerda, Elizabeth Bernardino   +5 more
doaj   +1 more source

Outpatient discharge management model: a strategy to promote continuity of care [PDF]

Revista Brasileira de Enfermagem
Objectives: to propose an outpatient discharge management model from specialized care to primary care to promote continuity of care for chronic conditions. Methods: action research with a qualitative approach.
Daniele Cristina dos Reis Bobrowec, Elizabeth Bernardino, Gisele Knop Aued, Jaqueline Dias do Nascimento Selleti, Maria Manuela Ferreira Pereira da Silva Martins, Camila Rorato, Keyla Cristina da Rocha Fracarolli, Lívia Cozer Montenegro   +7 more
doaj   +4 more sources

Improving coordination through information continuity: a framework for translational research

, 2016
BACKGROUND There is good evidence that coordination can have beneficial impacts on patient care and outcomes but the mechanisms by which coordination is to be achieved are poorly understood and rarely identified in relevant policies.
Banfield, Michelle, Gardner, Karen, Gillespie, James, McRae, Ian, Yen, Laurann   +4 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Patient-centered health care for infants: a qualitative analysis of mothers’ experiences and preferences [PDF]

, 2015
Objective: Nowhere is patient-centered care more important than in the vulnerable time of the first few weeks of a new-born’s life. However little is understood about mothers’ experiences and preferences with health care.
Miller, Amy, Miller, Joyce Elaine, Telford, A.C.J.   +2 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source