Results 81 to 90 of about 166,546,019 (294)

Quality of Care Transition for COVID-19 Patients in a University Hospital in Southern Brazil [PDF]

open access: yesRevista Brasileira de Enfermagem
Objective: To assess the quality of care transition from hospital to home for COVID-19 patients. Method: A cross-sectional study conducted at a University Hospital in Southern Brazil, involving 78 patients discharged after COVID-19 hospitalization. Data
Ana Cecilia Boeng   +5 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Outpatient discharge management model: a strategy to promote continuity of care [PDF]

open access: yesRevista Brasileira de Enfermagem
Objectives: to propose an outpatient discharge management model from specialized care to primary care to promote continuity of care for chronic conditions. Methods: action research with a qualitative approach.
Daniele Cristina dos Reis Bobrowec   +7 more
doaj   +4 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Continuity of Care

open access: yes, 2016
Background/purpose: Patient satisfaction and better outcomes are at the forefront of Medicare reimbursements under the 2010 enactment of the Affordable Care Act.
Dwyane Macias
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

DISCHARGE MANAGEMENT TO ENSURE CONTINUITY OF CARE: EXPERIENCE OF PORTUGUESE LIAISON NURSES

open access: yesCogitare Enfermagem, 2018
Objective: To describe the activities performed to ensure continuity of care by liaison nurses in hospital services. Method: Descriptive exploratory study with 107 nurses conducted from September 2016 to March 2017, in 15 hospitals in Portugal.
Maria Manuela Martins   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Avaliação da longitudinalidade em unidades de Atenção Primária à Saúde

open access: yesSaúde em Debate
Estudo para avaliar a efetividade da Atenção Primária à Saúde direcionada a crianças, por meio do atributo longitudinalidade, em unidades de saúde com e sem Estratégia Saúde da Família em município do Oeste do Paraná.
Bruna Regina Bratti Frank   +4 more
doaj   +1 more source

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