Results 111 to 120 of about 369,296 (309)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Experience with health care integration in Bidasoa integrated health organisation: development of the continuity of care unit/Experiencia de integración en la Organización Sanitaria Integrada Bidasoa: desarrollo de la Unidad de Continuidad Asistencial

International Journal of Integrated Care, 2012
Iñaki Berraondo Zabalegui
doaj   +3 more sources

Impacto del seguimiento al alta de Enfermería en Atención Primaria sobre los reingresos hospitalarios tempranos. Estudio observacional longitudinal

Atención Primaria
Resumen: Objetivo: Determinar la proporción de personas en las que se realiza el seguimiento al alta estando indicado.Diseño Estudio observacional longitudinal retrospectivo, con enfoque analítico.
Raquel Sánchez-Ruano, Pedro López-Paterna, César Alfonso García-Hernández, Ricardo Rodríguez-Barrientos, Elvira Herrero-Sanchox, Marcos Pascual-García, Milagros Rico-Blázquez   +6 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Challenges of Post-Discharge Follow-up in Psychiatric Patients in Isfahan Farabi Hospital: A Qualitative Study

Journal of Mazandaran University of Medical Sciences, 2022
Background and purpose: Comprehensive discharge program refers to providing education, follow-up and continuity of care. This issue is one of the requirements for the effectiveness of treatment in patients with mental health diseases. This study aimed at
Marzieh Javadi, Mohammad Mahdi Behzadnezhad, Mojtaba Alizade, Nasrin Sharbafchizade, Maryam Yaghoubi   +4 more
doaj  

Continuity of care in Swiss cancer patients

, 2018
17. Deutscher Kongress für Versorgungsforschung (DKVF)
Blozik, E, Näpflin, M, Bähler, C, Scherer, M   +3 more
openaire   +1 more source

Continuity and safety in care transitions: communication at the hospital/community care interface [PDF]

, 2010
In the health care setting, risks to patient safety may arise when there is poor written or verbal communication between personnel during times of care transition.
Kalucy, Elizabeth Carment, McIntyre, Ellen, Muecke, Sandy   +2 more
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source