Results 91 to 100 of about 13,838,869 (315)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Heterogeneous Impatience in a Continuous-Time Model [PDF]
In a continuous-time economy with complete markets, we show how the heterogeneity in the individual consumers' risk attitudes and impatience would affect the representative consumer's counterparts.
Hara, Chiaki
core +4 more sources
Computing continuous dynamic time warping of time series in polynomial time
Journal of Computational GeometryDynamic Time Warping is arguably the most popular similarity measure for time series, where we define a time series to be a one-dimensional polygonal curve.
Kevin Buchin +2 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Forecasting volatility: does continuous time do better than discrete time? [PDF]
In this paper we compare the forecast performance of continuous and discrete-time volatility models. In discrete time, we consider more than ten GARCH-type models and an asymmetric autoregressive stochastic volatility model.
Carles Bretó, Helena Veiga
core
Modelling commodity prices using continuous time models
, 2001 Nine continuous time models applied to metal prices are applied, following a recent study of these models on Eurocurrency interest rate data by Nowman (1998).
Helen Wang +3 more
core +1 more source
Time-decoupled high order continuous space-time finite element schemes for the heat equation [PDF]
, 2014 Copyright © by SIAMIn Comput. Methods Appl. Mech. Engrg., 190 (2001), pp. 6685—6708 Werder et al. demonstrated that time discretizations of the heat equation by a temporally discontinuous Galerkin finite element method could be decoupled by diagonalising
Kruse, C, Shaw, S
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Church Synthesis Problem over Continuous Time [PDF]
Logical Methods in Computer ScienceThe Church Problem asks for the construction of a procedure which, given a logical specification A(I,O) between input omega-strings I and output omega-strings O, determines whether there exists an operator F that implements the specification in the sense
Alexander Rabinovich, Daniel Fattal
doaj +1 more source
Continuous Time Bayesian Networks
CoRR, 2012 In this paper we present a language for finite state continuous time Bayesian networks (CTBNs), which describe structured stochastic processes that evolve over continuous time. The state of the system is decomposed into a set of local variables whose values change over time.
Uri Nodelman +2 more
openaire +3 more sources