Results 81 to 90 of about 2,688,493 (268)
On the Continuous-Time Complementarity Problem
Trends in Computational and Applied MathematicsThis work deals with solving continuous-time nonlinear complementarity problems defined on two types of nonempty closed convex cones: a polyhedral cone (positive octant) and a second-order cone.
M. R. C. do Monte, V. A. de Oliveira
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Time Course of Changes during Continuous High-Volume Hemodiafiltration
Общая реаниматология, 2008 Objective: to evaluate changes in the levels of cytokines, ferritin, and endothelin in the peripheral blood and filtrates of patients with multiple organ dysfunctions during continuous high-volume hemodiafiltration (CHVHDF).
N. V. Purlo +3 more
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Combat simulation using continuous time neural networks [PDF]
آیندهپژوهی دفاعی, 2018 This paper focuses on modeling the behavior of commanders in a combat simulation. A military mission is often associated with multiple conflicting goals, including task success, completion time, enemies’ elimination, and own forces survival.
Mohammad Moghaddas, Hamid Bigdeli
doaj
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Methods in Ecology and EvolutionBiodiversity monitoring is undergoing a revolution, with fauna observation data being increasingly gathered continuously over extended periods, through sensors like camera traps and acoustic recorders, or via opportunistic observations.
Léa Pautrel +3 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source