Results 121 to 130 of about 19,324,107 (306)

Analysing biodiversity observation data collected in continuous time: Should we use discrete‐ or continuous‐time occupancy models?

open access: yesMethods in Ecology and Evolution
Biodiversity monitoring is undergoing a revolution, with fauna observation data being increasingly gathered continuously over extended periods, through sensors like camera traps and acoustic recorders, or via opportunistic observations.
Léa Pautrel   +3 more
doaj   +1 more source

Combat simulation using continuous time neural networks [PDF]

open access: yesآینده‌پژوهی دفاعی, 2018
This paper focuses on modeling the behavior of commanders in a combat simulation. A military mission is often associated with multiple conflicting goals, including task success, completion time, enemies’ elimination, and own forces survival.
Mohammad Moghaddas, Hamid Bigdeli
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Continuous Time Chaotic Systems for Whale Optimization Algorithm

open access: yesAdvances in Electrical and Computer Engineering, 2018
Discrete time chaotic systems are often used instead of random number arrays in order to improve the convergence properties of optimization algorithms and prevent them to get stuck on local solutions.
TANYILDIZI, E., CIGAL, T.
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Existence of Financial Equilibria in Continuous Time with Potentially Complete Markets [PDF]

open access: yes
We prove that in smooth Markovian continuous-time economies with potentially complete asset markets, Radner equilibria with endogenously complete markets exist.Potentially complete market, Continuous-time financial market, Radner equilibrium, Itô ...
Frank Riedel, Frederik Herzberg
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Continuous-Time Overlapping Generations Models [PDF]

open access: yes
Age structured populations are studied in economics through overlapping generations models. These models allow for a realistic characterization of life-cycle behaviors and display intertemporal equilibrium that are not necessarily efficient. This article
Hippolyte D'Albis   +1 more
core  

Rex Bergstrom's contributions to continuous time macroeconometric modelling

open access: yes, 2009
This paper reviews the contributions of Rex Bergstrom to the development of continuous time dynamic disequilibrium macroeconomic modeling since the early 1960s.
Nowman, K.B.
core   +1 more source

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