Results 201 to 210 of about 13,838,869 (315)

Inferences and effect sizes for direct, indirect, and total effects in continuous-time mediation models. [PDF]

Psychol Methods
Pesigan IJA, Russell MA, Chow SM.
europepmc   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Continuous time crystal coupled to a mechanical mode as a cavity-optomechanics-like platform. [PDF]

Nat Commun
Mäkinen JT, Heikkinen PJ, Autti S, Zavjalov VV, Eltsov VB.   +4 more
europepmc   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Inferring effective networks of spiking neurons using a continuous-time estimator of transfer entropy. [PDF]

PLoS Comput Biol
Shorten DP, Priesemann V, Wibral M, Lizier JT.   +3 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Modeling gaze behavior with continuous-time markov chains to investigate social attention dynamics in autism. [PDF]

Sci Rep
Bruschetta R, Famà FI, Spadaro L, Leonardi E, Carrozza C, Aiello S, Campisi A, Mastrogiuseppe M, Campisi S, Chakrabarti B, Ruta L, Pioggia G, Gaetano A, Borri A, Tartarisco G, NEST Team.   +15 more
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

A theory of cerebellar learning as spike-based reinforcement learning in continuous time and space. [PDF]

PNAS Nexus
Kuriyama R, Yoshimura H, Yamazaki T.
europepmc   +1 more source

Continuous Modeling of Foreign Exchange Rate of USD versus TRY

This study aims to construct continuous-time autoregressive (CAR) model and continuous-time GARCH (COGARCH) model from discrete time data of foreign exchange rate of United States Dollar (USD) versus Turkish Lira (TRY).
Ari, Yakup, Unal, Gazanfer
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