Results 211 to 220 of about 19,324,107 (306)

Inferences and effect sizes for direct, indirect, and total effects in continuous-time mediation models. [PDF]

Psychol Methods
Pesigan IJA, Russell MA, Chow SM.
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Continuous time crystal coupled to a mechanical mode as a cavity-optomechanics-like platform. [PDF]

Nat Commun
Mäkinen JT, Heikkinen PJ, Autti S, Zavjalov VV, Eltsov VB.   +4 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Inferring effective networks of spiking neurons using a continuous-time estimator of transfer entropy. [PDF]

PLoS Comput Biol
Shorten DP, Priesemann V, Wibral M, Lizier JT.   +3 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

A theory of cerebellar learning as spike-based reinforcement learning in continuous time and space. [PDF]

PNAS Nexus
Kuriyama R, Yoshimura H, Yamazaki T.
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Modeling gaze behavior with continuous-time markov chains to investigate social attention dynamics in autism. [PDF]

Sci Rep
Bruschetta R, Famà FI, Spadaro L, Leonardi E, Carrozza C, Aiello S, Campisi A, Mastrogiuseppe M, Campisi S, Chakrabarti B, Ruta L, Pioggia G, Gaetano A, Borri A, Tartarisco G, NEST Team.   +15 more
europepmc   +1 more source