Results 81 to 90 of about 1,511,483 (263)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Existence of pure strategy equilibria in Bertrand-Edgeworth games with imperfect divisibility of money [PDF]

This paper incorporates imperfect divisibility of money in a price game where a given number of identical firms produce a homogeneous product at constant unit cost up to capacity.
De Francesco, Massimo A.
core   +1 more source

Partial actions of C*-quantum groups I: Restriction and Globalization

, 2018
Partial actions of groups on C*-algebras and the closely related actions and coactions of Hopf algebras received much attention over the last decades. They arise naturally as restrictions of their global counterparts to non-invariant subalgebras, and the
Kraken, Franziska, Quast, Paula, Timmermann, Thomas   +2 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

A Multi-Source Data Fusion-Based Method for Safety Monitoring of Construction Workers on Concrete Placement Surfaces

Buildings
Concrete placement surfaces are characterized by intensive construction processes, frequent equipment interactions, and strong spatial dynamics, which make it difficult to identify unsafe actions of construction workers in real time and to accurately ...
Jijiang Chen, Zijun Zhang, Xiao Sun, Yanyin Zhou, Yao Zhou, Yingjie Zhao, Jun Shi   +6 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Failure case study on reheater pipes in a subcritical unit served for a thermal power plant

Case Studies in Thermal Engineering
Leakage failure occurred in the reheater pipe of a subcritical unit after 9 years operation, but didn't reach the design lifespan. Multi test and analysis methods were applied to find the failure reason and mechanism.
Minglong Xu, Song Xue, Fengtao Hu, Zhengrong Jiang, Lixuan Zheng, Yi Ren, Zenong Li, Shaoxiang He, Rui Deng   +8 more
doaj   +1 more source

Exposure–response relationships for the ACGIH threshold limit value for hand-activity level: results from a pooled data study of carpal tunnel syndrome

Scandinavian Journal of Work, Environment & Health, 2014
OBJECTIVES: This paper aimed to quantify exposure–response relationships between the American Conference of Governmental Industrial Hygienists’ (ACGIH) threshold limit value (TLV) for hand-activity level (HAL) and incidence of carpal tunnel syndrome (CTS)
Jay M Kapellusch, Frederic E Gerr, Elizabeth J Malloy, Arun Garg, Carisa Harris-Adamson, Stephen S Bao, Susan E Burt, Ann Marie Dale, Ellen A Eisen, Bradley A Evanoff, Kurt T Hegmann, Barbara A Silverstein, Matthew S Theise, David M Rempel   +13 more
doaj   +1 more source

Existence of pure strategy equilibrium in Bertrand-Edgeworth games with imperfect divisibility of money [PDF]

This paper incorporates imperfect divisibility of money in a price game where a given number of identical firms produce a homogeneous product at constant unit cost up to capacity.
Massimo A. De Francesco
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source