Uncertainty-aware traction force microscopy. [PDF]
PLoS Computational BiologyTraction Force Microscopy (TFM) is a versatile tool to quantify cell-exerted forces by imaging and tracking fiduciary markers embedded in elastic substrates. The computations involved in TFM are often ill-conditioned, and data smoothing or regularization
Adithan Kandasamy +4 more
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Traction force microscopy – Measuring the forces exerted by cells
Micron, 2021 Cells generate mechanical forces (traction forces, TFs) while interacting with the extracellular matrix or neighbouring cells. Forces are generated by both cells and extracellular matrix (ECM) and transmitted within the cell-ECM or cell-cell contacts ...
Małgorzata Lekka +4 more
semanticscholar +6 more sources
Dynamic response of the cell traction force to osmotic shock [PDF]
Microsystems & Nanoengineering, 2023 Osmotic pressure is vital to many physiological activities, such as cell proliferation, wound healing and disease treatment. However, how cells interact with the extracellular matrix (ECM) when subjected to osmotic shock remains unclear.
Yongman Liu +6 more
doaj +3 more sources
Astigmatic traction force microscopy (aTFM) [PDF]
Nature Communications, 2021 Quantifying rapidly progressing three-dimensional forces generated by cells remains a major challenge in mechanobiology. Here, the authors show that combining traction force microscopy with astigmatic imaging permits sensitive out-of-plane force ...
Di Li +8 more
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A primer to traction force microscopy. [PDF]
J Biol Chem, 2022 Traction force microscopy (TFM) has emerged as a versatile technique for the measurement of single-cell-generated forces. TFM has gained wide use among mechanobiology laboratories, and several variants of the original methodology have been proposed ...
Zancla A +4 more
europepmc +4 more sources
Field Guide to Traction Force Microscopy. [PDF]
Cell Mol BioengTraction force microscopy (TFM) is a widely used technique to measure cell contractility on compliant substrates that mimic the stiffness of human tissues.
Denisin AK +3 more
europepmc +6 more sources
High-resolution assessment of multidimensional cellular mechanics using label-free refractive-index traction force microscopy [PDF]
Communications Biology, 2023 A critical requirement for studying cell mechanics is three-dimensional assessment of cellular shapes and forces with high spatiotemporal resolution. Traction force microscopy with fluorescence imaging enables the measurement of cellular forces, but it ...
Moosung Lee +7 more
doaj +3 more sources
Enhancing robustness, precision, and speed of traction force microscopy with machine learning. [PDF]
Biophys J, 2023 Traction patterns of adherent cells provide important information on their interaction with the environment, cell migration or tissue patterns and morphogenesis.
Kratz FS, Möllerherm L, Kierfeld J.
europepmc +2 more sources
Effects of nanopillars and surface coating on dynamic traction force. [PDF]
Microsyst Nanoeng, 2023 The extracellular matrix serves as structural support for cells and provides biophysical and biochemical cues for cell migration. Topography, material, and surface energy can regulate cell migration behaviors.
Cheng Y, Pang SW.
europepmc +2 more sources
What are the key factors influencing traction force in postless hip arthroscopy: a retrospective case-control study [PDF]
BMC Musculoskeletal DisordersBackground Perineal post countertraction during hip arthroscopy risks complications. Postless traction avoids the perineal post but requires understanding the factors influencing traction force to optimize safety. This study investigated how gender, body
Guanying Gao +4 more
doaj +2 more sources