Results 11 to 20 of about 1,881,967 (284)

Uncertainty-aware traction force microscopy. [PDF]

PLoS Computational Biology
Traction Force Microscopy (TFM) is a versatile tool to quantify cell-exerted forces by imaging and tracking fiduciary markers embedded in elastic substrates. The computations involved in TFM are often ill-conditioned, and data smoothing or regularization
Adithan Kandasamy, Yi-Ting Yeh, Ricardo Serrano, Mark Mercola, Juan C Del Alamo   +4 more
doaj   +6 more sources

Astigmatic traction force microscopy (aTFM) [PDF]

Nature Communications, 2021
Quantifying rapidly progressing three-dimensional forces generated by cells remains a major challenge in mechanobiology. Here, the authors show that combining traction force microscopy with astigmatic imaging permits sensitive out-of-plane force ...
Di Li, Huw Colin-York, Liliana Barbieri, Yousef Javanmardi, Yuting Guo, Kseniya Korobchevskaya, Emad Moeendarbary, Dong Li, Marco Fritzsche   +8 more
doaj   +7 more sources

Dynamic response of the cell traction force to osmotic shock [PDF]

Microsystems & Nanoengineering, 2023
Osmotic pressure is vital to many physiological activities, such as cell proliferation, wound healing and disease treatment. However, how cells interact with the extracellular matrix (ECM) when subjected to osmotic shock remains unclear.
Yongman Liu, Wenjie Wu, Shuo Feng, Ye Chen, Xiaoping Wu, Qingchuan Zhang, Shangquan Wu   +6 more
doaj   +2 more sources

Experimental and finite element analysis studies of a reduction-force reducing traction method for pelvic fracture surgeries

Medicine in Novel Technology and Devices, 2022
Pelvic fracture is among the most complicated fractures in traumatic orthopedics, with high mortality and morbidity rates. The main difficulty associated with the reduction surgery is significant muscle resistance.
Jixuan Liu, Ke Xu, Chunpeng Zhao, Gang Zhu, Yu Wang, Xinbao Wu, Wei Tian   +6 more
doaj   +3 more sources

A primer to traction force microscopy. [PDF]

J Biol Chem, 2022
Traction force microscopy (TFM) has emerged as a versatile technique for the measurement of single-cell-generated forces. TFM has gained wide use among mechanobiology laboratories, and several variants of the original methodology have been proposed. However, issues related to the experimental setup and, most importantly, data analysis of cell traction ...
Zancla A, Mozetic P, Orsini M, Forte G, Rainer A.   +4 more
europepmc   +3 more sources

What are the key factors influencing traction force in postless hip arthroscopy: a retrospective case-control study [PDF]

BMC Musculoskeletal Disorders
Background Perineal post countertraction during hip arthroscopy risks complications. Postless traction avoids the perineal post but requires understanding the factors influencing traction force to optimize safety. This study investigated how gender, body
Guanying Gao, Yize Han, Xiang Zhou, Jianquan Wang, Yan Xu   +4 more
doaj   +2 more sources

Traction force microscopy – Measuring the forces exerted by cells

Micron, 2021
Cells generate mechanical forces (traction forces, TFs) while interacting with the extracellular matrix or neighbouring cells. Forces are generated by both cells and extracellular matrix (ECM) and transmitted within the cell-ECM or cell-cell contacts involving focal adhesions or adherens junctions. Within more than two decades, substantial progress has
Tomasz Zielinski, Andrzej Kubiak, Malgorzata Lekka   +2 more
exaly   +3 more sources

Submicron traction-force mapping reveals mitochondrial regulation of nanoscale force coordination during rigidity sensing under oxidative stress [PDF]

Nano Convergence
Oxidative stress is closely associated with aging, fibrosis, and cancer progression, yet how oxidative stress affects rigidity sensing remains poorly understood.
Muhammad Anwar Ul Hassan, Seok Gi Kim, Dan Bi Im, Jung Seung Lee, Gwang Lee, Sungsu Park   +5 more
doaj   +2 more sources

Hip Rotation and Femoral Anteversion and Its Influence on Traction Force of the Pulled Limb in Hip Arthroscopy [PDF]

Orthopaedic Journal of Sports Medicine
Background: Several variables may affect the traction force during hip arthroscopy. Specifically, the degree of hip joint rotation may influence the magnitude of traction force during hip arthroscopy.
Guanying Gao MD, Jiayang Liu MD, Jingtao Duan MD, Jianquan Wang MD, Yan Xu MD   +4 more
doaj   +2 more sources

Validation tool for traction force microscopy

Computer Methods in Biomechanics and Biomedical Engineering, 2014
Traction force microscopy (TFM) is commonly used to estimate cells' traction forces from the deformation that they cause on their substrate. The accuracy of TFM highly depends on the computational methods used to measure the deformation of the substrate and estimate the forces, and also on the specifics of the experimental set-up.
Jorge-Penas, A., Munoz-Barrutia, A., Juan Pardo, Elena, Ortiz-de-Solorzano, C.   +3 more
openaire   +5 more sources