Results 21 to 30 of about 2,804,653 (355)

Super-Resolved Traction Force Microscopy (STFM) [PDF]

Nano Letters, 2016
Measuring small forces is a major challenge in cell biology. Here we improve the spatial resolution and accuracy of force reconstruction of the well-established technique of traction force microscopy (TFM) using STED microscopy. The increased spatial resolution of STED-TFM (STFM) allows a greater than 5-fold higher sampling of the forces generated by ...
Colin-York, H, Shrestha, D, Felce, JH, Waithe, D, Moeendarbary, E, Davis, SJ, Eggeling, C, Fritzsche, M   +7 more
openaire   +7 more sources

Identification of CD44 as a key engager to hyaluronic acid-rich extracellular matrices for cell traction force generation and tumor invasion in 3D. [PDF]

Matrix Biol
Mechanical properties of the extracellular matrix (ECM) critically regulate a number of important cell functions including growth, differentiation and migration.
Cheung BCH, Chen X, Davis HJ, Nordmann CS, Toth J, Hodgson L, Segall JE, Shenoy VB, Wu M.   +8 more
europepmc   +2 more sources

Traction force microscopy for understanding cellular mechanotransduction

BMB Reports, 2020
Under physiological and pathological conditions, mechanical forces generated from cells themselves or transmitted from extracellular matrix (ECM) through focal adhesions (FAs) and adherens junctions (AJs) are known to play a significant role in ...
S. Hur, J. Jeong, M. Ban, J. Park, J. Yoon, Yongsung Hwang   +5 more
semanticscholar   +4 more sources

TFMLAB: a MATLAB toolbox for 4D traction force microscopy [PDF]

SoftwareX, 2020
We present TFMLAB, a MATLAB software package for 4D (x;y;z;t) Traction Force Microscopy (TFM). While various TFM computational workflows are available in the literature, open-source programs that are easy to use by researchers with limited technical ...
Jorge Barrasa‐Fano, Apeksha Shapeti, Álvaro Jorge-Peñas, Mojtaba Barzegari, Jose A. Sanz‐Herrera, Hans Van Oosterwyck   +5 more
openalex   +2 more sources

Cellular traction forces increase during consecutive mechanical stretching following traction force attenuation

Journal of Biomechanical Science and Engineering, 2017
Adherent cells generate traction forces, which are generated by and transmitted along the actin cytoskeleton to the underlying external substrate via focal adhesions. These cell generated forces are fundamental for maintaining cell shape and driving cell
Akira TSUKAMOTO, Katie R. RYAN, Yusuke MITSUOKA, Katsuko S. FURUKAWA, Takashi USHIDA   +4 more
doaj   +3 more sources

Fluctuation-Based Super-Resolution Traction Force Microscopy

Nano Letters, 2020
Cellular mechanics play a crucial role in tissue homeostasis and are often misregulated in disease. Traction force microscopy is one of the key methods that has enabled researchers to study fundamental aspects of mechanobiology; however, traction force ...
Aki Stubb, Romain F. Laine, Mitro Miihkinen, Hellyeh Hamidi, Camilo Guzmán, Ricardo Henriques, Guillaume Jacquemet, J. Ivaska   +7 more
semanticscholar   +3 more sources

A traction force threshold signifies metastatic phenotypic change in multicellular epithelia

Soft Matter, 2019
Cancer metastasis has been believed as a genetically programmed process that is commonly marked by biochemical signals. Here using extracellular matrix control of cellular mechanics, we establish that cellular force threshold can also mark in vitro ...
Yao Zhang, Xuechen Shi, Tiankai Zhao, Changjin Huang, Qiong Wei, Xin Tang, Lorraine C. Santy, M. Taher A. Saif, Sulin Zhang   +8 more
openalex   +3 more sources

Mapping Collective Forces of Lung Cancer Spheroids Using Traction Force Microscopy. [PDF]

Biotechnol Bioeng
Zhang Q, Chen J, Zhang Z, Liu W.
europepmc   +3 more sources

Dimensional memory in glioblastoma mechanics: Traction force analysis of cells cultured in 2D versus 3D collagen environments. [PDF]

Bioact Mater
Khan M, Kollenz P, Fritzenschaft M, Taheri F, Colombo F, Blumberg JW, Schlotterose L, Schwarz US, Leal-Egaña A, Selhuber-Unkel C.   +9 more
europepmc   +2 more sources

Semi-Empirical Time-Dependent Parameter of Shear Strength for Traction Force between Deep-Sea Sediment and Tracked Miner

Sensors, 2022
Based on our direct shear creep experiment and the direct shear rheological constitutive model, a semi-empirical time-dependent parameter of the shear strength is obtained by Mohr–Coulomb shear strength theory, and different time-dependent traction force
Wei Yi, Feng Xu
doaj   +1 more source