Results 151 to 160 of about 8,164,188 (290)
Continuous dependence on modelling for temperature-dependent bidispersive flow
Proceedings of the Royal Society A, 2017 F. Franchi, Roberta Nibbi, B. Straughan
semanticscholar +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Continuous dependence and fixed points for some multivalued operators
Journal of Numerical Analysis and Approximation Theory, 1997 In this paper we extend the notion of \(I^0\)-continuity and uniform \(I^0\)-continuity from [2] to set-valued operators. For families of such operators we prove (semi)continuity of the fixed point sets.
Eduard Kirr, Adrian Petrușel
doaj
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Continuous dependence of solutions for indefinite semilinear elliptic problems
Electronic Journal of Differential Equations, 2013 We consider the superlinear elliptic problem $$ -\Delta u + m(x)u = a(x)u^p $$ in a bounded smooth domain under Neumann boundary conditions, where $m \in L^{\sigma}(\Omega)$, $\sigma\geq N/2$ and $a\in C(\overline{\Omega})$ is a sign changing ...
Elves A. B. Silva, Maxwell L. Silva
doaj
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Continuous dependence of ergodic limits
The discrete and continuous parameter forms of the mean ergodic theorem conclude that as N --> [infinity] or [tau] --> [infinity]. The ergodic limit P is shown to depend continuously on the operator T in the discrete case or on the infinitesimal ...
Goldstein, Jerome A. +1 more
core
Continuous dependence of delta on epsilon as a selection property
, 2005 We give a negative answer to a question of Malesic and Repovs, about continuous selections of the modulus of continuity. We also provide a shorter proof for a theorem of the same authors, which generalizes a classical result about continuous dependence ...
COSTANTINI C, MARCONI, UMBERTO
core
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source