Results 151 to 160 of about 358,060 (302)
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Continuous dependence of solutions for indefinite semilinear elliptic problems
Electronic Journal of Differential Equations, 2013 We consider the superlinear elliptic problem $$ -\Delta u + m(x)u = a(x)u^p $$ in a bounded smooth domain under Neumann boundary conditions, where $m \in L^{\sigma}(\Omega)$, $\sigma\geq N/2$ and $a\in C(\overline{\Omega})$ is a sign changing ...
Elves A. B. Silva, Maxwell L. Silva
doaj
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Forecasting volatility: does continuous time do better than discrete time? [PDF]
In this paper we compare the forecast performance of continuous and discrete-time volatility models. In discrete time, we consider more than ten GARCH-type models and an asymmetric autoregressive stochastic volatility model.
Carles Bretó, Helena Veiga
core
Structural stability for double-diffusion Brinkman fluid with Soret effect
Boundary Value ProblemsThis paper considers the double diffusive Brinkman flow in a semi-infinite pipe. By establishing a priori estimates of the solutions and setting an appropriate “energy” function, we not only obtain the continuous dependence and convergence of the ...
Yuanfei Li
doaj +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
A Simple Test for the Absence of Covariate Dependence in Hazard Regression Models [PDF]
, 2004 This paper extends commonly used tests for equality of hazard rates in a two-sample or k-sample setup to a situation where the covariate under study is continuous.
Bhattacharjee, Arnab +3 more
core
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
CONTINUOUS DEPENDENCE RESULTS FOR A CLASS OF EVOLUTION INCLUSIONS
, 1992 PAPAGEORGIOU, NS
core +1 more source