Results 131 to 140 of about 8,164,188 (290)
Solutions to boundary-value problems for nonlinear differential equations of fractional order
we discuss the existence, uniqueness and continuous dependence of solutions for a boundary value problem of nonlinear fractional differential equation.
doaj
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Continuous dependence of solutions of elliptic BVPs on parameters [PDF]
The continuous dependence of solutions for a certain class of elliptic PDE on functional parameters is studied in this paper. The main result is as follow: the sequence \(\{x_k\}_{k\in N}\) of solutions of the Dirichlet problem discussed here ...
Aleksandra Orpel
doaj
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Inverse boundary value problems at the boundary—continuous dependence
We use the methods of microlocal analysis to give a new proof of a theorem of Kohn and Vogelius, showing that the boundary values of a continuous isotropic conductivity can be recovered from voltage and current measurements at the boundary.
Sylvester, John, Uhlmann, Gunther
core +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Dependence of the optical continuous spectrum of quasars on their red-shift [PDF]
Dependence of optical continuous spectrum of quasi-stellar sources on red ...
Kardashev, N. S., Komberg, B. V.
core
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source

