Results 121 to 130 of about 8,164,188 (290)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Continuous dependence of solutions of operator equations. I

open access: yes, 1977
Continuous dependence of the solutions of the operator equation x = T x + z x = Tx + z in a topological vector space is the main subject of the paper. We find sufficient and necessary conditions
Zvi Artstein
core   +1 more source

Some basic theorems on difference-differential equations

open access: yesElectronic Journal of Differential Equations, 2008
In this paper some basic theorems on the existence, uniqueness and continuous dependence of solutions of a certain difference-differential equation are established.
Baburao G. Pachpatte
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Qualitative Analysis of a Class of Fractional Functional Differential Systems with Feedback Control

open access: yesFractal and Fractional
In this paper, we investigate a class of fractional functional differential systems with feedback control, in which the fractional derivatives are interpreted in the Caputo sense.
Kheria M. O. Msaik   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Lagged Duration Dependence in Mixed Proportional Hazard Models [PDF]

open access: yes
We study the non-parametric identification of a mixed proportional hazard model with lagged duration dependence when data provide multiple outcomes per individual or stratum.
Matteo PICCHIO
core  

Continuous dependence for $ p $-Laplace equations with varying operators

open access: yes
For the following Neumann problem in a ball {-Delta(p)u + u(p-1) = u(q-1) in B, u > 0, u radial in B, partial derivative u/partial derivative nu = 0 on partial derivative B, with 1 < p < q < infinity, we prove continuous dependence on p, for ...
Noris, Benedetta   +2 more
core   +1 more source

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