Results 81 to 90 of about 358,060 (302)

UNIVERSITY OF CAMBRIDGE Numerical Analysis Reports

open access: yes, 1997
The purpose of this work is to consider an initial value problem for neutral functional differential equations with state dependent and vanishing delays.
England Cb Ew   +2 more
core  

Stability of entropy solutions for Levy mixed hyperbolic-parabolic equations

open access: yesElectronic Journal of Differential Equations, 2011
We analyze entropy solutions for a class of Levy mixed hyperbolic-parabolic equations containing a non-local (or fractional) diffusion operator originating from a pure jump Levy process.
Kenneth H. Karlsen, Suleyman Ulusoy
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

On the Continuous Dependence of Solutions of Nonlinear Equations

open access: yesJournal of Mathematical Analysis and Applications, 1995
The author considers the boundary value problem (1) \(x' (t)= f(x, t)+ y(t)\), \(L(x)= r\), where \(f: \mathbb{R}^m \times [0, 1]\to \mathbb{R}^m\), \(L: C^0 ([ 0,1], \mathbb{R}^m)\to \mathbb{R}^m\) and \(y: [0, 1]\to \mathbb{R}^m\) are continuous, \(r\in \mathbb{R}^m\). The existence, the uniqueness and the continuous dependence of solutions to (1) is
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

A new class of copulas with tail dependence and a generalized tail dependence estimator [PDF]

open access: yes
We present a new family of copulas (generalized mean copulas) which is positive comprehensive and allows for upper tail dependence. It includes the Spearman copula and a specific Fréchet copula as special cases.
Fischer, Matthias J., Hinzmann, Gerd
core  

A Study of Structural Stability on the Bidispersive Flow in a Semi-Infinite Cylinder

open access: yesAxioms
We consider the bidispersive flow with nonlinear boundary conditions in a bounded region. By using the differential inequality technique, we get the bound for the L4-norm of the salinity which plays an important role.
Yuanfei Li
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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