Results 91 to 100 of about 358,060 (302)

Coupled system of a fractional order differential equations with weighted initial conditions

Open Mathematics, 2019
Here, a coupled system of nonlinear weighted Cauchy-type problem of a diffre-integral equations of fractional order will be considered. We study the existence of at least one integrable solution of this system by using Schauder fixed point Theorem.
El-Sayed Ahmed M. A., Abd El-Salam Sheren A.   +1 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Well-posedness and maximum principles for lattice reaction-diffusion equations

Advances in Nonlinear Analysis, 2017
Existence, uniqueness and continuous dependence results together with maximum principles represent key tools in the analysis of lattice reaction-diffusion equations.
Slavík Antonín, Stehlík Petr, Volek Jonáš   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Fastness and continuous dependence in front propagation in Fisher-KPP equations

, 2009
We investigate the continuous dependence of the minimal speed of propagation and the profile of the corresponding travelling wave solution of Fisher-type reaction-diffusion equations θ_t = (D(θ)θ_x)_x + f(θ) with respect to both the reaction term f and ...
ARIAS M., CAMPOS J., MARCELLI, Cristina
core   +1 more source

Structural Stability of Pseudo-Parabolic Equations for Basic Data

Mathematical and Computational Applications
This article investigates the spatial decay properties and continuous dependence on the basic geometric structure. Assuming that the total potential energy is bounded and the homogeneous Dirichlet condition is satisfied on the side of the solution within
Yanping Wang, Yuanfei Li
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Lagged Duration Dependence in Mixed Proportional Hazard Models [PDF]

We study the non-parametric identification of a mixed proportional hazard model with lagged duration dependence when data provide multiple outcomes per individual or stratum.
Matteo PICCHIO
core  

Continuous dependence for backward parabolic operators with Log-Lipschitz coefficients

, 2009
We prove continuous dependence on Cauchy data for a backward parabolic operator whose coefficients are Log-Lipschitz continuous in time.
DEL SANTO, DANIELE, PRIZZI, Martino
core   +1 more source

Fredholm type integrodifferential equation on time scales

Electronic Journal of Differential Equations, 2010
The aim of this article is to study some basic qualitative properties of solutions to Fredholm type integrodifferential equations on time scales. A new integral inequality with explicit estimate on time scales is obtained and used to establish the ...
Deepak B. Pachpatte
doaj