Results 91 to 100 of about 8,164,188 (290)

A Study of Structural Stability on the Bidispersive Flow in a Semi-Infinite Cylinder

open access: yesAxioms
We consider the bidispersive flow with nonlinear boundary conditions in a bounded region. By using the differential inequality technique, we get the bound for the L4-norm of the salinity which plays an important role.
Yuanfei Li
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Multivariate measures of positive dependence [PDF]

open access: yes
In this paper a set of desirable properties for measures of positive dependence of ordered n-tuples of continuous random variables (n >= 2) is proposed and a class of multivariate positive dependence measures is introduced. We consider the comonotonicity
Marta Cardin
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Coupled system of a fractional order differential equations with weighted initial conditions

open access: yesOpen Mathematics, 2019
Here, a coupled system of nonlinear weighted Cauchy-type problem of a diffre-integral equations of fractional order will be considered. We study the existence of at least one integrable solution of this system by using Schauder fixed point Theorem.
El-Sayed Ahmed M. A.   +1 more
doaj   +1 more source

Continuous dependence of solutions of generalized linear ordinary differential equations on a parameter [PDF]

open access: yes, 2007
summary:We present here the problem of continuous dependence for generalized linear ordinary differential equations in the case when uniform convergence is violated. This work continues research of M. Ashordia (1993) and M. Tvrdý (2002)
Halas, Zdeněk
core   +1 more source

Fredholm type integrodifferential equation on time scales

open access: yesElectronic Journal of Differential Equations, 2010
The aim of this article is to study some basic qualitative properties of solutions to Fredholm type integrodifferential equations on time scales. A new integral inequality with explicit estimate on time scales is obtained and used to establish the ...
Deepak B. Pachpatte
doaj  

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