Results 61 to 70 of about 3,211,981 (291)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Continuous Flow Optimisation of the Pudovik Reaction and Phospha-Brook Rearrangement Using DBN
ReactionsFlow chemistry has shown significant versatility over the last two decades, offering advantages in efficiency, scalability, and sustainability.
Joseph Dean +4 more
doaj +1 more source
Micro reactor and flow chemistry for industrial applications in drug discovery and development
Green Processing and Synthesis, 2012 In this review, case studies focused on syntheses of active pharmaceutical ingredients, intermediates and lead compounds are reported employing micro reactors and continuous flow technology in areas such as medicinal chemistry, chemical development and ...
Baraldi Patricia T., Hessel Volker
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Microfluidic Device on Fused Silica for Raman Spectroscopy of Liquid Samples
BiosensorsWater testing is becoming increasingly important due to dangerous phenomena such as Harmful Algal Blooms (HABs). Commonly, the content of a water sample is measured for the detection, monitoring and control of these events.
Celia Gómez-Galdós +7 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2021 Electrocatalytic dehydrogenative C(sp3)–H/C(sp)–H cross-coupling of tetrahydroisoquinolines with terminal alkynes has been achieved in a continuous-flow microreactor through 2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPO)/copper relay catalysis.
Bin Guo, Hai-Chao Xu
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Surge vs. continuous-flow irrigation
California Agriculture, 1987 Not available – first paragraph follows: A primary goal of good irrigation management is to minimize deep percolation of water (infiltration exceeding the irrigation requirement) while replenishing soil water in the plant root zone along the entire ...
D Goldhamer, M Alemi, R Phene
doaj
Dynamic Transitions and Baroclinic Instability for 3D Continuously Stratified Boussinesq Flows
, 2018 The main objective of this article is to study the nonlinear stability and dynamic transitions of the basic (zonal) shear flows for the three-dimensional continuously stratified rotating Boussinesq model.
Wang, Shouhong, Şengül, Taylan
core +1 more source