Comparison of ibuprofen release from minitablets and capsules containing ibuprofen: β-Cyclodextrin complex [PDF]
NOTICE: this is the author’s version of a work that was accepted for publication in European Journal of Pharmaceutics and Biopharmaceutics. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting ...
Amidon +31 more
core +1 more source
Changing the daily injection of glatiramer acetate to a monthly long acting product through designing polyester-based polymeric microspheres [PDF]
Introduction: Glatiramer acetate (GA) is a newly emerged therapeutic peptide to reduce the frequency of relapses in multiple sclerosis (MS). Despite its good performance in controlling MS, it is not widely used due to daily or biweekly subcutaneous ...
Fatima Molavi +2 more
doaj +1 more source
Mechanistic modelling of infrared mediated energy transfer during the primary drying step of a continuous freeze-drying process [PDF]
Conventional pharmaceutical freeze-drying is an inefficient and expensive batch-wise process, associated with several disadvantages leading to an uncontrolled end product variability. The proposed continuous alternative, based on spinning the vials during freezing and on optimal energy supply during drying, strongly increases process efficiency and ...
Van Bockstal, Pieter-Jan +6 more
openaire +3 more sources
A green, rapid, and facile synthesis method of activated carbon was developed and optimized using 50 nm MgO nanoparticle (NP)-based pore templating in tandem with an integrated drying and carbonization-activation heat treatment.
Mark Adam FERRY +3 more
doaj +1 more source
Freeze-dried mucoadhesive polymeric system containing pegylated lipoplexes : towards a vaginal sustained released system for siRNA [PDF]
peer reviewedTopical vaginal sustained delivery of siRNA presents a significant challenge due to the short residence time of formulations. Therefore, a drug delivery system capable to adhere to the vaginal mucosa is desirable, as it could allow a ...
Furst, Tania +7 more
core +1 more source
High-resolution three-dimensional views of membrane-associated clathrin and cytoskeleton in critical-point-dried macrophages. [PDF]
We obtained high-resolution topographical information about the distribution of clathrin and cytoskeletal filaments on cytoplasmic membrane surfaces of macrophages spreading onto glass coverslips by both critical-point drying of broken-open cells and ...
Aggeler, J, Takemura, R, Werb, Z
core +1 more source
Inclusion Compound of Efavirenz and γ-Cyclodextrin: Solid State Studies and Effect on Solubility
Efavirenz is an antiretroviral drug of widespread use in the management of infections with human immunodeficiency virus type 1 (HIV-1). Efavirenz is also used in paediatrics, but due to its very poor aqueous solubility the liquid formulations available ...
Susana Santos Braga +3 more
doaj +1 more source
Evaluation of spin freezing versus conventional freezing as part of a continuous pharmaceutical freeze-drying concept for unit doses [PDF]
Spin-freezing as alternative freezing approach was evaluated as part of an innovative continuous pharmaceutical freeze-drying concept for unit doses. The aim of this paper was to compare the sublimation rate of spin-frozen vials versus traditionally frozen vials in a batch freeze-dryer, and its impact on total drying time.
De Meyer, Laurens +5 more
openaire +2 more sources
Abstract The article considers the problem of improving the quality of semi-finished vegetables and the possibility of optimizing and automating this process. The processes of cleaning calibrated crushed lumpy materials are analyzed depending on the physicomechanical and chemical properties of the processed materials, with elements of ...
R Khrameshin, A Khrameshin
openaire +1 more source
Collagen-hyaluronic acid scaffolds for adipose tissue engineering. [PDF]
Three-dimensional (3-D) in vitro models of the mammary gland require a scaffold matrix that supports the development of adipose stroma within a robust freely permeable matrix. 3-D porous collagen-hyaluronic acid (HA: 7.5% and 15%) scaffolds were produced
Cameron, RE +4 more
core +2 more sources

