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Lyophilization: The process and industrial use [PDF]

open access: yesHemijska Industrija, 2004
This article presents a general overview of lyophilization and discusses the underlying principles of the process through the basics of: formulation, freezing, primary drying and secondary drying.
Pržić Dejan S.   +2 more
doaj   +2 more sources

Impact of seven conservation methods on the nutritional value, phytochemical composition, and chemical antioxidant capacity of Terfezia boudieri and Tirmania nivea from Southeastern Tunisia [PDF]

open access: yesFrontiers in Pharmacology
IntroductionDesert truffles (Terfezia boudieri and Tirmania nivea) are edible fungi valued for their nutritional and nutraceutical properties. However, the effects of post-harvest preservation on their bioactive composition and health-related quality ...
Nadia Ghanney   +6 more
doaj   +2 more sources

Lyophilization process optimization and molecular dynamics simulation of mRNA-LNPs for SARS-CoV-2 vaccine

open access: yesnpj Vaccines, 2023
Some studies have shown that lyophilization significantly improves the stability of mRNA-LNPs and enables long-term storage at 2–8 °C. However, there is little research on the lyophilization process of mRNA-lipid nanoparticles (LNPs).
Mingyuan Li   +14 more
doaj   +1 more source

Effect of Lyophilization on Stability of PEG-Protein Conjugate: A Case Study with Peginterferon alfa-2b

open access: yesBrazilian Journal of Pharmaceutical Sciences, 2023
The purpose of the present study was to develop stable lyophilized formulation of peginterferon alfa-2b which is acquiescent to the short lyophilization process.
Patel Chintan, Patel Gayatri
doaj   +1 more source

The function of uridine diphosphate glucose pyrophosphorylase in the lyophilization-stress response of Lactobacillus acidophilus

open access: yesAnnals of Microbiology, 2022
Purpose Uridine diphosphate glucose pyrophosphorylase (UGPase) plays an important role in glucose metabolism, catalyzing the reversible formation and decomposition of UDP-glucose (UDPG).
Chaoran Xia   +6 more
doaj   +1 more source

Limited influence of marine sediment lyophilization on prokaryotic community structure assessed via amplicon sequencing: an example from environmentally contrasted sediment layers in Toulon harbor (France) [PDF]

open access: yesPeerJ, 2021
Sediment lyophilization is a common process that allows for long-term conservation and sharing of marine sediments for multiple downstream analyses. Although it is often used for geochemical studies, the effects of lyophilization on prokaryotic taxonomic
Benjamin Misson   +2 more
doaj   +2 more sources

Production of chitosan scaffolds by lyophilization or electrospinning: which is better for peripheral nerve regeneration?

open access: yesNeural Regeneration Research, 2021
Both lyophilization and electrospinning are commonly used to make chitosan scaffolds. However, it remains unknown which method is better for cell growth. In this study, we established the following groups: (1) lyophilization group—chitosan scaffolds were
Yu-Xuan Wu   +3 more
doaj   +1 more source

Effects of Lyophilization on the Metabonomic Phenotypes of Human Biofluids Characterized with NMR Analysis

open access: yesChinese Journal of Magnetic Resonance, 2020
Sample pretreatment is essential for metabonomic analysis. Lyophilization (freeze-drying) is widely used for sample pretreatment to remove solvent, especially water, prior to nuclear magnetic resonance (NMR) and/or mass spectrum (MS) analysis.
LIU Si, AN Yan-peng, TANG Hui-ru
doaj   +1 more source

Lyoprotectant Formulation and Optimization of the J-Aggregates Astaxanthin/BSA/Chitosan Nanosuspension

open access: yesBiomolecules, 2023
Astaxanthin is a carotenoid with excellent antioxidant activity. However, this small lipid-soluble molecule is insoluble in water and has low stability. Although this situation can be improved when astaxanthin is prepared as a nanosuspension, the aqueous
Yingyuan Zhao   +6 more
doaj   +1 more source

LYOPHILIZATION EFFECT ON PRODUCTIVITY OF BUTANOL-PRODUCING STRAINS [PDF]

open access: yesBiotechnologia Acta, 2016
Investigation of lyophilization effect on the productivity of butanol-producing strains was the aim of our research. For this purpose we used butanol-producing strains; technical glycerol; biomass of switchgrass Panicum virgatum L.
O. O. Tigunova   +4 more
doaj   +1 more source

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