Results 11 to 20 of about 50,534 (301)

Recent Development of Optimization of Lyophilization Process

Journal of Chemistry, 2019
The objective of this review is to survey the development of the optimization of lyophilization. The optimization study of the lyophilizer has been roughly developing by the order of (i) trial-and-error approach, (ii) process modeling using mathematical ...
Hidenori Kawasaki, Toshinori Shimanouchi, Yukitaka Kimura   +2 more
doaj   +2 more sources

OPTIMIZATION OF BACTERIAL LYOPHILIZATION PROCESS: INFLUENCE OF CULTIVATION AND LYOPHILIZATION PARAMETERS ON PROBIOTIC SURVIVAL RATE

Siberian Journal of Life Sciences and Agriculture
Background. The preservation of bacterial cultures plays an important role in scientific research and industrial production, both food and medical.
Mariia S. Ashikhmina, Vladislav S. Filozop, Mikhail O. Volodarskiy, Sviatlana A. Ulasevich, Ekaterina V. Skorb   +4 more
doaj   +2 more sources

Lyophilization

, 2020
Due to the thermolability of food and pharmaceutical products the drying process cannot be performed at high temperature; lyophilization replaces then standard drying units taking advantage of sublimation instead of evaporation. Being freeze drying a batch operation, a suitable model is used to assess the operating residence time for given operating ...
Di Pretoro A., Manenti F.
core   +4 more sources

Effect of freezing temperature on rate of survival of lactococcus cultures during lyophilization

Пищевые системы
The important component in the activities of the collection of starter microorganisms is the preservation of the pool of the strains valuable for industrial production.
I. V. Kucherenko, E. V. Kuraeva, E. S. Masegnaya   +2 more
doaj   +2 more sources

Modification of the Physicochemical Properties of Active Pharmaceutical Ingredients via Lyophilization

Pharmaceutics, 2023
Bioavailability is an important biopharmaceutical characteristic of active pharmaceutical ingredients (APIs) that is often correlated with their solubility in water. One of the methods of increasing solubility is freeze drying (lyophilization).
Amir Taldaev, Denis I. Pankov, Roman P. Terekhov, Anastasia K. Zhevlakova, Irina A. Selivanova   +4 more
doaj   +2 more sources

Alterations in Carbohydrate Quantities in Freeze-Dried, Relative to Fresh or Frozen Maize Leaf Disks

Biomolecules, 2023
For various reasons, leaves are occasionally lyophilized prior to storage at −80 °C and preparing extracts. Soluble carbohydrate identity and quantity from maize leaf disks were ascertained in two separate years using anion exchange HPLC with pulsed ...
Lynnette M. A. Dirk, Tianyong Zhao, John May, Tao Li, Qinghui Han, Yumin Zhang, Mohammad R. Sahib, Allan Bruce Downie   +7 more
doaj   +1 more source

A Comprehensive Design Approach for Injectable Manufacturing Processes considering New Technologies and Operational Aspects

Journal of Chemical Engineering of Japan, 2023
An approach is proposed to comprehensively design the injectable manufacturing process considering various options such as batch and continuous operation modes, multi-use and single-use technology (SUT) equipment, and production sequences.
Masahiro Yamada, Sara Badr, Yusuke Hayashi, Kenichi Zenitani, Kokichi Kubota, Hayao Nakanishi, Hirokazu Sugiyama   +6 more
doaj   +1 more source

Manufacture of a Stable Lyophilized Formulation of the Live Attenuated Pertussis Vaccine BPZE1

Vaccines, 2020
Current pertussis vaccines protect against disease, but not against colonization by and transmission of Bordetella pertussis, whereas natural infection protects against both.
Marcel Thalen, Anne-Sophie Debrie, Loic Coutte, Dominique Raze, Ken Solovay, Keith Rubin, Nathalie Mielcarek, Camille Locht   +7 more
doaj   +1 more source

Monitoring of the primary drying of a lyophilization process in vials [PDF]

, 2009
An innovative and modular system (LyoMonitor) for monitoring the primary drying of a lyophilization process in vials is illustrated: it integrates some commercial devices (pressure gauges, moisture sensor and mass spectrometer), an innovative balance and
Galan, M., Parvis, Marco, Fissore, Davide, Barresi, Antonello, Pisano, Roberto, Galan M., Vallan, Alberto, Velardi, S.A., Rasetto, Valeria, Velardi S. A.   +9 more
core   +1 more source

Lyophilization-Free Approach to the Fabrication of Conductive Polymer Foams Enabling Photo-Thermo-Electrical-Induced Cell Differentiation under Global Illumination

, 2023
In this study, we fabricate conductive polymer (PEDOT:PSS) foams with tunable density and mechanical properties via a new and efficient lyophilization-free method and use asymmetric acid treatment to create a PEDOT:PSS scaffold with asymmetric light ...
Peng Tao (1338780), Benwei Fu (6312884), Tao Deng (158002), Chengyi Song (1437862), Shun Chen (745877), Wendong Liu (507488), Cuilan Hou (1765774), Zhihui Lei (12106308), Wen Shang (302434)   +8 more
core   +1 more source