Results 21 to 30 of about 40,837 (264)

Recent Development of Optimization of Lyophilization Process

Journal of Chemistry, 2019
The objective of this review is to survey the development of the optimization of lyophilization. The optimization study of the lyophilizer has been roughly developing by the order of (i) trial-and-error approach, (ii) process modeling using mathematical ...
Hidenori Kawasaki, Toshinori Shimanouchi, Yukitaka Kimura   +2 more
doaj   +1 more source

Effect of pretreatment, lyophilization parameters and different cryoprotectants on the efficiency of probiotic freeze-drying immobilization [PDF]

Hemijska Industrija
Lyophilization is an excellent process to increase the shelf life of food products or preserve probiotics. Living cells prefer mild conditions, and any deviation (vacuum, high or low temperatures) leads to cell damage.
Krunić Tanja Ž., Osmokrović Andrea M.
doaj   +1 more source

Untargeted Plant Metabolomics: Evaluation of Lyophilization as a Sample Preparation Technique

Metabolites, 2023
Lyophilization is a common method used for stabilizing biological samples prior to storage or to concentrate extracts. However, it is possible that this process may alter the metabolic composition or lead to the loss of metabolites.
Christina Maisl, Maria Doppler, Bernhard Seidl, Christoph Bueschl, Rainer Schuhmacher   +4 more
doaj   +1 more source

Modification of the Physicochemical Properties of Active Pharmaceutical Ingredients via Lyophilization

Pharmaceutics, 2023
Bioavailability is an important biopharmaceutical characteristic of active pharmaceutical ingredients (APIs) that is often correlated with their solubility in water. One of the methods of increasing solubility is freeze drying (lyophilization).
Amir Taldaev, Denis I. Pankov, Roman P. Terekhov, Anastasia K. Zhevlakova, Irina A. Selivanova   +4 more
doaj   +1 more source

Conservation of Microorganisms of Biotechnological Interest

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Food Science and Technology
Thirty strains of microorganisms from the National Collection of Nonpathogenic Microorganisms (NCNM) were used as study objects (actinobacteria, bacteria, and micromycetes).
Tamara SÎRBU, Cristina MOLDOVAN, Valerian SLANINA, Maxim BÎRSA   +3 more
doaj   +1 more source

A strategy to promote the convenient storage and direct use of polyhydroxybutyrate-degrading Bacillus sp. JY14 by lyophilization with protective reagents

Microbial Cell Factories, 2023
Background Bioplastics are attracting considerable attention, owing to the increase in non-degradable waste. Using microorganisms to degrade bioplastics is a promising strategy for reducing non-degradable plastic waste.
Su Hyun Kim, Nara Shin, Suk Jin Oh, Jeong Hyeon Hwang, Hyun Jin Kim, Shashi Kant Bhatia, Jeonghee Yun, Jae-Seok Kim, Yung-Hun Yang   +8 more
doaj   +1 more source

Development of Lyophilized Gemini Surfactant-Based Gene Delivery Systems: Influence of Lyophilization on the Structure, Activity and Stability of the Lipoplexes

Journal of Pharmacy & Pharmaceutical Sciences, 2012
Purpose. Cationic gemini surfactants have been studied as non-viral vectors for gene therapy. Clinical applications of cationic lipid/DNA lipoplexes are restricted by their instability in aqueous formulations.
Waleed Mohammed-Saeid, Deborah Michel, Anas El-Aneed, Ronald E Verrall, Nicholas H Low, Ildiko Badea   +5 more
doaj   +1 more source

Effect of freezing temperature on rate of survival of lactococcus cultures during lyophilization

Пищевые системы
The important component in the activities of the collection of starter microorganisms is the preservation of the pool of the strains valuable for industrial production.
I. V. Kucherenko, E. V. Kuraeva, E. S. Masegnaya   +2 more
doaj   +1 more source

OPTIMIZATION OF BACTERIAL LYOPHILIZATION PROCESS: INFLUENCE OF CULTIVATION AND LYOPHILIZATION PARAMETERS ON PROBIOTIC SURVIVAL RATE

Siberian Journal of Life Sciences and Agriculture
Background. The preservation of bacterial cultures plays an important role in scientific research and industrial production, both food and medical.
Mariia S. Ashikhmina, Vladislav S. Filozop, Mikhail O. Volodarskiy, Sviatlana A. Ulasevich, Ekaterina V. Skorb   +4 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source