Results 31 to 40 of about 28,705 (244)
Electrochemistry, 2022 A green, rapid, and facile synthesis method of activated carbon was developed and optimized using 50 nm MgO nanoparticle (NP)-based pore templating in tandem with an integrated drying and carbonization-activation heat treatment.
Mark Adam FERRY +3 more
doaj +1 more source
AAPS OpenNucleic acid therapeutics have emerged as the third major class of therapeutics, following small molecules and antibodies. Lipid nanoparticles (LNPs) serve as the leading platform for nucleic acid delivery.
Zixuan Zhen +4 more
doaj +1 more source
Quantum TeknikaThe potential of natural resources in tropical countries is very diverse. one of them is the abundant agricultural products. but there are some obstacles in the post-harvest cycle and the continuous availability when the harvest season ends.
Mirza Yusuf +4 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Thermal Imaging as a Noncontact Inline Process Analytical Tool for Product Temperature Monitoring during Continuous Freeze-Drying of Unit Doses [PDF]
Analytical Chemistry, 2018 Freeze-drying is a well-established technique to improve the stability of biopharmaceuticals which are unstable in aqueous solution. To obtain an elegant dried product appearance, the temperature at the moving sublimation interface Ti should be kept below the critical product temperature Ti,crit during primary drying.
Pieter-Jan Van Bockstal +4 more
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Study on the vacuum freeze-drying of banana and impact on powder properties
Case Studies in Thermal EngineeringThis research evaluated vacuum freeze-drying (VFD) for banana slices in terms of drying behavior, energy, cost, color, rehydration, shrinkage, pH and °Brix, microstructure, and thermal images. Additionally, powder properties were investigated.
Onur Taskin
doaj +1 more source
Inclusion Compound of Efavirenz and γ-Cyclodextrin: Solid State Studies and Effect on Solubility
Molecules, 2021 Efavirenz is an antiretroviral drug of widespread use in the management of infections with human immunodeficiency virus type 1 (HIV-1). Efavirenz is also used in paediatrics, but due to its very poor aqueous solubility the liquid formulations available ...
Susana Santos Braga +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source