Results 61 to 70 of about 223,531 (304)

Evaluating the impact of annealing and radiative cooling on a PEGylated peptide formulation subjected to continuous spin-freeze-drying

open access: yesAAPS Open
Annealing is commonly used in traditional lyophilization processes to crystallize solutes, improve drying efficiency and reduce cake heterogeneity, yet its integration into continuous spin-freeze-drying has not yet been reported.
Zarah Schaal   +7 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Study on the vacuum freeze-drying of banana and impact on powder properties

open access: yesCase Studies in Thermal Engineering
This research evaluated vacuum freeze-drying (VFD) for banana slices in terms of drying behavior, energy, cost, color, rehydration, shrinkage, pH and °Brix, microstructure, and thermal images. Additionally, powder properties were investigated.
Onur Taskin
doaj   +1 more source

Effect of curing conditions and harvesting stage of maturity on Ethiopian onion bulb drying properties [PDF]

open access: yes, 2019
The study was conducted to investigate the impact of curing conditions and harvesting stageson the drying quality of onion bulbs. The onion bulbs (Bombay Red cultivar) were harvested at three harvesting stages (early, optimum, and late ...
Adgo, Enyew   +8 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Multi-Point Wireless Temperature Sensing System for Monitoring Pharmaceutical Lyophilization

open access: yesFrontiers in Chemistry, 2018
This work presents the design and evaluation of a fully wireless, multi-point temperature sensor system as a Process Analytical Technology (PAT) for lyophilization.
Xiaofan Jiang   +5 more
doaj   +1 more source

The effect of sample drying temperature on marine particulate organic carbon composition [PDF]

open access: yes, 2018
Author Posting. © The Author(s), 2018. This is the author's version of the work. It is posted here under a nonexclusive, irrevocable, paid-up, worldwide license granted to WHOI. It is made available for personal use, not for redistribution.
Galy, Valier   +4 more
core   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte   +13 more
wiley   +1 more source

Use of Highly Dispersed Silica in Biotechnology of Complex Probiotic Product Based on Bifidobacteria

open access: yesInnovative Biosystems and Bioengineering, 2022
Background. The probiotics immobilization technology is one of the most effective ways for controlled and continuous delivery of viable cells into the intestine.
Svitlana Danylenko   +4 more
doaj   +1 more source

Neodymium recovery by chitosan/iron(III) hydroxide [ChiFer(III)] sorbent material: Batch and column systems [PDF]

open access: yes, 2018
A low cost composite material was synthesized for neodymium recovery from dilute aqueous solutions. The in-situ production of the composite containing chitosan and iron(III) hydroxide (ChiFer(III)) was improved and the results were compared with raw ...
Demey Cedeño, Hary   +5 more
core   +3 more sources

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