Results 91 to 100 of about 2,873,110 (291)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Digital Transformation Meets Process Improvement: Driving Enterprise Continuous Efficiency-Seeking
Engineering ProceedingsAutomation and digitization have gained every aspect of our life. Performance and digital are precepted as twins, and thus process improvement (i.e., performance continuous seek) has fatally met digital.
Najib Ouradi, Rajaa Saidi, Walid Cherif
doaj +1 more source
Case studies to enhance online student evaluation: Central Queensland University – The big red button [PDF]
, 2015 Student feedback is imperative to the improvement of courses and teaching. As stated by Harvey, “to make an effective contribution to internal improvement processes, views of students need to be integrated into a regular and continuous cycle of analysis,
Fleming, Julie +7 more
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Continuous Improvement in Process Safety Education
Chemical Engineering Transactions, 2019 The importance of continuous improvement is emphasized in this paper from the perspectives of process safety education in general and university process safety courses in particular.
Paul Amyotte, Faisal Khan, Yene Irvine
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Methods and Conditions for Achieving Continuous Improvement of Processes [PDF]
In the early twentieth century, the Taylor model improved, in a spectacular maner the efficiency of the production processes. This allowed obtaining high productivity by low-skilled workers, but used in large number in the execution of production ...
Ana-Maria GRIGORE +2 more
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The Buddhist perspective of continual improvement
Kelaniya Journal of Management, 2016 Continual Improvement (CI) is closely linked to Japanese quality management. As the CI concepts were developed in a strong Buddhist culture in the background, a remarkable similarity can be seen between CI and Buddhism.
T. Jayawardane, A. C. De Alwis
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