Results 71 to 80 of about 2,873,110 (291)

THE COMPLEXITY OF LEAN [PDF]

open access: yesSEA: Practical Application of Science, 2022
Today, lean is a popular research field. Nothing proves its popularity better than the fact that it is now used not only at production companies, but also at service companies, and its appearance in office environments is getting more and more common ...
Mihály BOGDÁN, Péter POPOVICS
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Scott & White Healthcare: Opening Up and Embracing Change to Improve Performance [PDF]

open access: yes, 2010
Offers a case study of a multispeciality system with the attributes of an ideal healthcare delivery system as defined by the Fund. Describes a culture of continuous improvement, collaboration and peer accountability, and a comprehensive approach to ...
Douglas McCarthy, Kimberly Mueller
core  

The Abelian Higgs Model in Three Dimensions with Improved Action [PDF]

open access: yes, 1999
We study the Abelian Higgs Model using an improved form of the action in the scalar sector. The subleading corrections are carefully analysed and the connection between lattice and continuous parameters is worked out.
Dimopoulos, P.   +2 more
core   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Patient Experience at Discharge: A Quality Improvement Study in an Armed Forces Hospital, Saudi Arabia

open access: yesJournal of Patient Experience
Over the past decade, the health sector of Saudi Arabia has been undergoing a major transformation. This pilot research aimed to improve the patient experience (PX) at discharge by at least 2 scores within 2 years at a King Abdul Aziz Armed Forces ...
Noha Almohaisen BDS, SBARD, MHQS, CPXP, CPHQ, EMBA(c)   +4 more
doaj   +1 more source

The Imperative of Continuous Improvement: Enhancing Human Resources in Schools

open access: yesJournal of Islamic Education Research
The research aims to reveal the truth and conclusions about an object at the Nurul Jadid Vocational School Institution. The subject is human resources.
Hasan Baharun, Abdullah, Holifah
doaj   +1 more source

Discrete Innovation, Continuous Improvement, and Competitive Pressure [PDF]

open access: yes
Does competitive pressure foster innovation? In addressing this important question, prior studies ignored a distinction between discrete innovation aiming at entirely new technology and continuous improvement consisting of numerous incremental ...
Ghosh, Arghya   +2 more
core   +1 more source

Roadmap for Next-Generation Accountability Systems [PDF]

open access: yes, 2011
Offers a framework for designing and implementing state accountability systems that enable consistent, aligned goals to ensure college- and career-readiness; valid measurement, support, and interventions; transparent reporting; and continuous ...

core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

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