Results 61 to 70 of about 2,873,110 (291)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

A Comprehensive Review on Bigels as a Potential Replacement to Solid Fat in Food Applications

Journal of Food Quality
Bigels, composed of hydrogels and oleogels, are emerging as innovative materials with significant potential in the food industry. This review explores the application of bigels in various food contexts, including conventional and novel meats, plant-based
Wasiya Farzana, Sneha Mahesh, Sachin Sharma, Irshaan Syed, Gholamreza Abdi, Rituja Upadhyay   +5 more
doaj   +1 more source

Identification of Barriers Towards Change and Proposal to Institutionalize Continuous Improvement Programs in Manufacturing Operations

Journal of Technology Management & Innovation, 2011
A multi case research unfolded into a study in a sample of Brazilian manufacturing companies concerning their Continuous Improvement (CI) program in manufacturing operations. Stakeholders interviews and performance analyses were conducted. The study aims
Alvair Silveira Torres Jr., Ana Maria Gati   +1 more
doaj   +1 more source

Testing of Illicit Drugs in Seized Materials and Biological Specimens [PDF]

Guidance for ...
Continuous Improvement, United Nations
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

THE EVALUATION OF THE BUSINESS PLAN OF UNIVERSITY ALUMNI USING CONTINUOUS IMPROVEMENT MINDSET CONCEPT

Review of Management and Entrepreneurship, 2019
In the past, producers think only about the outcome of production, however, producers began to shift, as the need of customers must be in line with the purpose of the product or service that is produced.
Anastasia Filiana Ismawati
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Guiding Transformation: How Medical Practices Can Become Patient-Centered Medical Homes [PDF]

, 2012
Describes in detail eight change concepts as a guide to transforming a practice into a patient-centered medical home, including engaged leadership, quality improvement strategy, continuous and team-based healing relationships, and enhanced ...
Ed Wagner, Jonathan R. Sugarman, Kathryn Phillips, Katie Coleman, Robert J. Reid   +4 more
core  

Effective Student Outcomes Assessment Plan Reform Strong Undergraduate Curriculum Plan [PDF]

, 2019
The undergraduate curriculum committee from the Bob L. Herd Department of Petroleum Engineering at Texas Tech University has made significant modifications that were determined by a systematic student outcomes assessment plan.
Disque, Bethany, Gamadi, Talal D., Heinze, Lloyd, Watson, Marshal   +3 more
core   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source