Results 151 to 160 of about 5,191,391 (257)

Global Health Education Revamped: Implementation of a Cross-Cultural Virtual Elective Through Continuous Improvement Methods. [PDF]

open access: yesMed Sci Educ, 2023
Alam T   +13 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Continuous Improvement of Digital Health Applications Linked to Real-World Performance Monitoring: Safe Moving Targets? [PDF]

open access: yesMayo Clin Proc Digit Health, 2023
Gilbert S   +4 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Dispersion of continuous improvement and its impact on continuous improvement

open access: yes, 2008
An integrated continuous improvement (CI) strategy is asserted to comprise an essential element of the struggle for many firms to maintain international competitive advantage (Bessant and Caffyn, 1997 and Chapman et al 2002).
Sloan, Keith   +2 more
core  

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Five Decades of Pancreas Transplantation at the University Hospital of Zurich-A Story of Continuous Improvement and Success. [PDF]

open access: yesClin Transplant
Frey MC   +11 more
europepmc   +1 more source

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