Results 31 to 40 of about 2,847,157 (340)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Reducing hospital-acquired pressure injuries

open access: yesBMJ Open Quality, 2019
Hospital-acquired pressure injury is a common preventable condition. Our hospital is a 144-bed governmental hospital in the Kingdom of Saudi Arabia that was found to have a 7.5% prevalence of hospital-acquired pressure injury in 2016.
Yasser K Al-Otaibi   +2 more
doaj   +1 more source

A study into continuous improvement initiative sustainability [PDF]

open access: yes, 2013
The idea of continuous improvement is familiar to most managers and there are many examples of how its use can increase a company’s overall performance.
Butler, Michael   +2 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Continuous Quality Improvement as a Central Tenet of TQM: History and Current Status

open access: yesKvalita Inovácia Prosperita, 2016
Purpose: The great promise of continual quality improvement advocated by early quality gurus like Deming and Juran has not been fully realized. This paper explores the reasons for the limited success of implementation and institutionalization of ...
Behrooz Lahidji, Walter Tucker
doaj   +1 more source

Towards a new approach of continuous process improvement based on CMMI and PMBOK [PDF]

open access: green, 2021
Yassine Rdiouat   +3 more
openalex   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Airlines Seat Pricing with Seat Upgrading

open access: yesMultimodal Transportation, 2022
Pricing optimization is key to the airlines’ profitability. Oftentimes, the premium cabin demand falls short of the seat capacity, making economy cabin seat upgrading a common practice.
Yihua Li   +2 more
doaj   +1 more source

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