Results 81 to 90 of about 768,012 (158)

Design of a rapid, continuous, small-scale device for creating dry powders from concentrated suspensions containing active pharmaceutical ingredients [PDF]

, 2011
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, June 2011."February 2011." Cataloged from PDF version of thesis.Includes bibliographical references (p.
Correll, Eric Owen
core  

Early detection of capping risk in pharmaceutical compacts [PDF]

, 2018
Capping is a common mechanical defect in tablet manufacturing, exhibited during or after the compression process. Predicting tablet capping in terms of process variables (e.g.
Cetinkaya, Centin, Dave, Vivek S., Hoag, Stephen W., Vallabh, Chaitanya Krishna Prasad, Xu, Xiaochi   +4 more
core   +1 more source

Analysis and control of a scalar conservation law modeling a highly re-entrant manufacturing system

, 2010
In this paper, we study a scalar conservation law that models a highly re-entrant manufacturing system as encountered in semi-conductor production.
Shang, Peipei, Wang, Zhiqiang
core   +3 more sources

Mechanistic Modeling of Continuous Lyophilization for Biopharmaceutical Manufacturing

Advanced Science
Abstract Lyophilization (aka freeze drying) is a typical process in (bio)pharmaceutical manufacturing used for improving the stability of various drug products, including its recent applications to mRNA vaccines. While extensive efforts are dedicated to shifting the (bio)pharmaceutical industry toward continuous manufacturing, the ...
Prakitr Srisuma, Gang Chen, Richard D. Braatz   +2 more
openaire   +3 more sources

The Continuous Process of Ethylsilicate Manufacture

Chemical engineering, 1963
A continuous process of manufacturing Ethylsilicate (Si (OEt) 4) from EtOH and Tetrachlorosilane (SiCL4) was developed.This reaction is the rapidly consecutive reaction, remarkably exothermic, and generating a large quantity of HCL. Furthermore, the formation of the byproduct (polysilicate) increases when the reaction temperature rises above 0°C, and ...
openaire   +2 more sources

Continuous Manufacturing of Recombinant Drugs: Comprehensive Analysis of Cost Reduction Strategies, Regulatory Pathways, and Global Implementation

Pharmaceuticals
The biopharmaceutical industry is undergoing a fundamental transformation from traditional batch manufacturing to continuous manufacturing (CM) for recombinant drugs and biosimilars, driven by regulatory support through the International Council for ...
Sarfaraz K. Niazi
doaj   +1 more source

Manufacturing Performance Reporting For Continuous Quality Improvement [PDF]

, 1992
Recently many plants have implemented the new manufacturing strategy of continuous quality improvement. The central hypothesis in this paper is that the implementation of a policy of continuous quality improvement results in a shift in the management ...
Banker, Rajiv D., Potter, Gordon S., Schroeder, Roger G.   +2 more
core  

Exploiting the Fc base of IgG antibodies to create functional nanoparticle conjugates

Scientific Reports
The structures of the Fc base of various IgG antibodies have been examined with a view to understanding how this region can be used to conjugate IgG to nanoparticles.
Mohammed M. Al Qaraghuli, Karina Kubiak-Ossowska, Valerie A. Ferro, Paul A. Mulheran   +3 more
doaj   +1 more source

Investigating the Effects of Mixing Dynamics on Twin-Screw Granule Quality Attributes via the Development of a Physics-Based Process Map

Pharmaceutics
Twin-screw granulation (TSG) is an emerging continuous wet granulation technique that has not been widely applied in the industry due to a poor mechanistic understanding of the process.
Lalith Kotamarthy, Subhodh Karkala, Ashley Dan, Andrés D. Román-Ospino, Rohit Ramachandran   +4 more
doaj   +1 more source

Process analytical technology for continuous manufacturing of solid-dosage forms [PDF]

, 2015
De Beer, Thomas, De Leersnyder, Fien, Fonteyne, Margot, Remon, Jean Paul, Van Snick, Bernd, Vercruysse, Jurgen, Vervaet, Chris   +6 more
core   +1 more source