Results 71 to 80 of about 3,007,727 (303)

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

open access: yesAdvanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang   +10 more
wiley   +1 more source

A return to nursing rounds : person centred or a task too far?

open access: yes, 2015
Nursing rounds have been reintroduced in many clinical areas in order to improve nursing care and patient outcomes focusing on patient safety and satisfaction. The term 'nursing round' is used to describe several different practices and models in nursing
Brunero, Scott (R19180)   +2 more
core  

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

open access: yesAdvanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu   +5 more
wiley   +1 more source

Microglial TSPAN4‐Dependent Migrasomes Promote Pathological Retinal Neovascularization via Immune‐Vascular Crosstalk

open access: yesAdvanced Science, EarlyView.
Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu   +12 more
wiley   +1 more source

Construction of quality evaluation index system of hospital⁃community linkage continuous nursing for patients with inflammatory bowel disease

open access: yesHuli yanjiu
ObjectiveTo construct a standardized,scientific and systematic quality evaluation index system of hospital⁃community linkage continuous nursing for patients with inflammatory bowel disease.MethodsBased on the three⁃dimensional quality structure model,the
LU Xueping   +5 more
doaj  

PLXDC2 siRNA‐Mediated Intervention Attenuates Microglial Senescence Through cGAS‐STING Signaling

open access: yesAdvanced Science, EarlyView.
PLXDC2 was identified as a microglial target in Parkinson's disease through human and mouse single‐cell analyses. Ferritin‐armed biomimetic nanovesicles delivered PLXDC2 siRNA, deferoxamine, and CeO2 nanoparticles across the blood–brain barrier, reducing cGAS‐STING activation, iron burden, oxidative stress, and senescence in microglia, thereby ...
Heyue Lu   +13 more
wiley   +1 more source

Assessment tool for nursing student computer competencies

open access: yes, 2009
The full text of this article is not available in SOAR. WSU users can access the article via commercial databases licensed by University Libraries: http://libcat.wichita.edu/vwebv/holdingsInfo?bibId=1332112.
Elder, Betty L., Koehn, Mary L.
core  

The Effects of Learning Styles and Nursing Professional Attitude on Problem-Solving Ability among Nursing Students

open access: yes, 2017
Purpose: The effects of learning styles and nursing professional attitude on the problem-solving ability among nursing students were explained. Methods: A cross-sectional descriptive study was performed with 245 nursing students who completed self-report
고일선
core   +1 more source

An Injectable and Self‐Reinforced Piezoelectric Hydrogel for Irregular Bone Defects Regeneration: Dynamic Epigenetic Regulation Approach

open access: yesAdvanced Science, EarlyView.
An injectable and self‐reinforcing RSF‐based piezoelectric hydrogel conforms to irregular bone defects and progressively strengthens in situ, overcoming the trade‐off between injectability and mechanical stability. Mechanical loading generates bioelectrical cues that promote P300‐mediated H3K9 acetylation and upregulate PTH1R expression, thereby ...
Yu‐Kai Huang   +15 more
wiley   +1 more source

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