Results 91 to 100 of about 522,687 (294)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

An improved algorithm for evaluating trellis phase codes [PDF]

open access: yes
A method is described for evaluating the minimum distance parameters of trellis phase codes, including CPFSK, partial response FM, and more importantly, coded CPM (continuous phase modulation) schemes. The algorithm provides dramatically faster execution
Mulligan, M. G., Wilson, S. G.
core   +1 more source

Analysis of Imperfections in Practical Continuous-Variable Quantum Key Distribution

open access: yes, 2012
As quantum key distribution becomes a mature technology, it appears clearly that some assumptions made in the security proofs cannot be justified in practical implementations. This might open the door to possible side-channel attacks.
A. Winter   +7 more
core   +3 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Adaptive procedure for automatic modulation recognition

open access: yesJournal of Telecommunications and Information Technology, 2004
An adaptive procedure for automatic modulation recognition is described. With it the automatic modulation classification and recognition of radio communication signals with a priori unknown parameters is possible effectively.
Ferdinand Liedtke
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Design and Implementation of a Multi-Mode Telemetry Transmitter

open access: yesSensors
In space applications, the required levels of performance and reliability drive up hardware costs. Reducing the efforts related to device development and validation may help balance the budget.
Francesco Silino   +5 more
doaj   +1 more source

CODED CONTINUOUS PHASE MODULATION FOR TACTICAL COMMUNICATIONS

open access: yes, 2014
Taktik alıcı-vericilerin çeşitli gerekliliklerini yerine getirmek askeri haberleşmenin en yaygın sorunlarından biridir. Farklı modülasyon, kodlama ve geniş spektrum teknikleri bu ihtiyaçları karşılamalıdır.FSK, askeri telsiz ve taktiksel dalga formları için en yaygın olarak kullanılan modülasyon tekniği olsada, devamlı faz modülasyonu (CPM) spektral ...
openaire   +2 more sources

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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