Results 81 to 90 of about 512,105 (392)

Impact of early continuous positive airway pressure in the delivery room (DR-CPAP) on neonates < 1500 g in a low-resource setting: a protocol for a pilot feasibility and acceptability randomized controlled trial [PDF]

Background Preterm birth is the leading cause of childhood mortality, and respiratory distress syndrome is the predominant cause of these deaths. Early continuous positive airway pressure is effective in high-resource settings, reducing the rate of ...
Burgoine, Kathy, Denis, Amorut, Grace, Abongo, Hagmann, Cornelia Franziska, Hewitt-Smith, Adam, Loe, Kate, Martha, Muduwa, Nakiyemba, Alice, Namuyonga, Judith, Napyo, Agnes, Okello, Francis, Olupot-Olupot, Peter, Ssenkusu, John M, Wandabwa, Julius   +13 more
core   +1 more source

Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles

Advanced Science, EarlyView.
Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon, Patricia Perez Schmidt, Nicolo Panini, Francesca Caruso, Martina B. Violatto, Naths Grazia Sukubo, Alberto Martinez‐Serra, Charlotte Blanche Ekalle‐Soppo, Annalisa Morelli, Giulia Yuri Moscatiello, Chiara Grasselli, Alessandro Corbelli, Fabio Fiordaliso, Joe Kelk, Laura Petrosilli, Giuseppe d'Orazio, Ruth Mateu Ferrando, Ariadna Verdaguer Ferrer, Cristina Fornaguera, Luigi Lay, Stefano Fumagalli, Sandro Recchia, Marco P. Monopoli, Laura Polito, Paolo Bigini, Giovanni Sitia   +25 more
wiley   +1 more source

Use of continuous positive airway pressure reduces airway reactivity in adults with asthma [PDF]

, 2012
Asthma is characterised by airway hyperreactivity, which is primarily treated with β-adrenergic bronchodilators and anti-inflammatory agents. However, mechanical strain during breathing is an important modulator of airway responsiveness and we have ...
Busk, Michael, Busk, Nancy, Gunst, Susan J., Hutchins, Janet, Puntenney, Paula, Tepper, Robert S., Yu, Zhangsheng   +6 more
core   +1 more source

PRMT1 Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF‐κB Signaling

Advanced Science, EarlyView.
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran, Yideul Jeong, Suwoo Kim, Ji Eun Yeom, Jinwoo Lee, Wonhwa Lee, Gyu‐Un Bae, Jong‐Sun Kang   +7 more
wiley   +1 more source

Continuous positive airway pressure for term and ≥34+0 weeks’ gestation newborns at birth: A systematic review

Resuscitation Plus, 2022
Background: Respiratory distress is common during transition after birth, but the effect of continuous positive airway pressure applied in the delivery room has not been systematically evaluated in spontaneously breathing term and ≥34+0 weeks’ gestation ...
Birju A. Shah, Jorge G. Fabres, Tina A. Leone, Georg M. Schmölzer, Edgardo G. Szyld   +4 more
doaj  

Annexin A3 Represses Endothelial Permeability and Inflammation During Sepsis via Actin Cytoskeleton Modulation

Advanced Science, EarlyView.
Annexin A3 (ANXA3) plays an endogenous protective role in endothelial dysfunction in sepsis by stabilizing the actin cytoskeleton, modulating cell permeability, and inhibiting pATF2/CD62E inflammatory signaling. Abstract Increased endothelial permeability and a dysregulated inflammatory response play key roles in organ damage in sepsis.
Manyu Xing, Shuang Liang, Wei Cao, Qulian Guo, Wangyuan Zou   +4 more
wiley   +1 more source

Efficacy and safety of non‐pharmacological interventions for endotracheal suctioning pain in preterm infants: A systematic review

Nursing Open, Volume 10, Issue 2, Page 424-434, February 2023., 2023
Abstract Aim To review and analyse the evidence on the efficacy and safety of non‐pharmacological interventions for preterm infants to relieve endotracheal suctioning (ES) pain. Design A systematic review per the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines. Methods Six databases were searched with a retrieval strategy.
Qian Cai, Wen Luo, You Zhou, Yue Yin, Kai Zhu, Huan Shi, Yuexia Liao   +6 more
wiley   +1 more source

Out-of-hospital noninvasive ventilation: epidemiology, technology and equipment

Pediatric Reports, 2012
Noninvasive ventilation has been utilized successfully in the pre- and out-of-hospital settings for a variety of disorders, including respiratory distress syndrome in neonates, neurologic and pulmonary diseases in infants and children, and heart failure ...
John Scott Baird, Thyyar M. Ravindranath
doaj   +1 more source

Extraction of Pulmonary Airway in CT Scans Using Deep Fully Convolutional Networks [PDF]

arXiv, 2022
Accurate, automatic and complete extraction of pulmonary airway in medical images plays an important role in analyzing thoracic CT volumes such as lung cancer detection, chronic obstructive pulmonary disease (COPD), and bronchoscopic-assisted surgery navigation.
arxiv  

Diagnosing and Treating Sleep Apnea in Patients With Acute Cerebrovascular Disease [PDF]

, 2018
Background Obstructive sleep apnea ( OSA ) is common among patients with acute ischemic stroke and transient ischemic attack. We evaluated whether continuous positive airway pressure for OSA among patients with recent ischemic stroke or transient ...
Austin, Charles, Bravata, Dawn M., Concato, John, Ferguson, Jared, Fleck, J.D., Iannone, Lynne, Ivan, Cristina S., Lampert, Rachel, Matthias, Marianne S., Miech, Edward J., Ofner, Susan, Qin, Li, Radulescu, Radu, Sico, Jason, Taylor, Stanley, Tobias, Lauren, Vaz Fragoso, Carlos A., Williams, Linda S., Won, Christine, Yaggi, H. Klar   +19 more
core   +1 more source