Results 121 to 130 of about 583,715 (304)

Manufacturing Performance Reporting For Continuous Quality Improvement

open access: yes, 1992
Recently many plants have implemented the new manufacturing strategy of continuous quality improvement. The central hypothesis in this paper is that the implementation of a policy of continuous quality improvement results in a shift in the management ...
Schroeder, Roger G.   +2 more
core  

Information logistics for continuous dependability improvement

open access: yes, 2014
Purpose – The purpose of this paper is to describe an information logistic framework for continuous dependability improvement that is applied within Sweden to improve the operational availability performance of the railway system.Design/methodology ...
Norrbin, Per,, Söderholm, Peter,
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Role of Quality Management in Pharmaceutical Development: Evidence from Islamabad and Lahore [PDF]

open access: yes
The aim of this paper is to investigate the employee’s perceptions of the impact, of Total Quality Management (TQM), on their roles within the organization and how they perceived the effectiveness of the quality processes in Pakistan Pharmaceutical ...
Tariq Mehmood   +2 more
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Cell design, management and continuous improvement [PDF]

open access: yes, 1997
A cellular manufacturing system is a shop floor that has been organised into groups of dissimilar machines producing groups of similar parts. Each group of machines is called a cell and each group of parts is called a part family. The main advantage of a
Baker, Robert Peter
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Automated Web Applications Testing [PDF]

open access: yes
Unit tests are a vital part of several software development practices and processes such as Test-First Programming, Extreme Programming and Test-Driven Development.
Alexandru Dan CAPRITA
core  

Evaluating the Impact of Critical Factors in Agile Continuous Delivery Process: A System Dynamics Approach

open access: yes, 2014
Continuous Delivery is aimed at the frequent delivery of good quality software in a speedy, reliable and efficient fashion – with strong emphasis on automation and team collaboration. However, even with this new paradigm, repeatability of project outcome
Akerele, O, Dixon, MB, Ramachandran, M
core   +1 more source

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