Results 51 to 60 of about 516,459 (254)

Patient Experience at Discharge: A Quality Improvement Study in an Armed Forces Hospital, Saudi Arabia

open access: yesJournal of Patient Experience
Over the past decade, the health sector of Saudi Arabia has been undergoing a major transformation. This pilot research aimed to improve the patient experience (PX) at discharge by at least 2 scores within 2 years at a King Abdul Aziz Armed Forces ...
Noha Almohaisen BDS, SBARD, MHQS, CPXP, CPHQ, EMBA(c)   +4 more
doaj   +1 more source

A Comparison of Quality Improvement Methods in Health System [PDF]

open access: yesTaṣvīr-i salāmat, 2013
Background and Objectives : Quality improvement is defined as improving process performance and maintaining improved results. Improvement methods and quality tools are two important factors of CQI projects.
Mostafa Farah Bakhsh
doaj  

A Continuous Quality Improvement (CQI) Curriculum for Residents

open access: yesMedEdPORTAL, 2007
Introduction Continuous quality improvement (CQI) has become an ever-increasingly important part of the healthcare industry, both in terms of its effect on improving the care of patients, as well as on improving the educational environment.
Alexander Djuricich
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Continuous Quality Improvement [PDF]

open access: yesInternational Journal of Engineering Sciences & Research Technology, 2021
Mary C. Zonsius, Kerry A. Milner
openaire   +2 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

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