Results 71 to 80 of about 7,456,500 (294)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Record Statistics of Continuous Time Random Walk
, 2011 The statistics of records for a time series generated by a continuous time random walk is studied, and found to be independent of the details of the jump length distribution, as long as the latter is continuous and symmetric.
Sabhapandit, Sanjib
core +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Continuous-Time Quantum Algorithms for Unstructured Problems
, 2013 We consider a family of unstructured problems, for which we propose a method for constructing analog, continuous-time quantum algorithms that are more efficient than their classical counterparts.
Hen, Itay
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Church Synthesis Problem over Continuous Time [PDF]
Logical Methods in Computer ScienceThe Church Problem asks for the construction of a procedure which, given a logical specification A(I,O) between input omega-strings I and output omega-strings O, determines whether there exists an operator F that implements the specification in the sense
Alexander Rabinovich, Daniel Fattal
doaj +1 more source
On Equilibrium Prices in Continuous Time [PDF]
, 2008 We combine general equilibrium theory and theorie generale of stochastic processes to derive structural results about equilibrium state ...
Frank Riedel +3 more
core +6 more sources
Continuous-Time Multivariate Analysis
Journal of Computational and Graphical StatisticsThe starting point for much of multivariate analysis (MVA) is an n × p data matrix whose n rows represent observations and whose p columns represent variables. Some multivariate datasets, however, may be best conceptualized not as n discrete p-variate observations, but as p curves or functions defined on a common time interval.
Biplab Paul +3 more
openaire +2 more sources